Category Archives: Epidemiology

Prevalence and burden of toxoplasma gondii infection in HIV-infected people: A systematic review and meta-analysis

2017

BACKGROUND: Worldwide, 30% of the world’s population have antibodies to the intracellular protozoan parasite Toxoplasma gondii and about 36.7 million people are infected with HIV, but little is known about...

A global review of HIV self-testing: Themes and implications

2017

HIV self-test kits may have the potential to increase testing rates around the globe, and thereby lead to reductions in HIV-related incidence and mortality. However, the effectiveness of these self-test...

The impact of sharps injuries on student nurses: A systematic review

2016

AIMS AND OBJECTIVES: The purpose of this review was to discover the impact of sharps injuries in the student nurse population. BACKGROUND: Much is known and reported about sharps injuries...

HIV and orthopaedics: Musculoskeletal manifestations and outcomes

2016

Advances in combined antiretroviral therapy (cART) in recent years have transformed HIV infection into a chronic disease when treatment is available, increasing a patient’s life expectancy and the chances that...

Deploying aptameric sensing technology for rapid pandemic monitoring

2015

The genome of virulent strains may possess the ability to mutate by means of antigenic shift and/or antigenic drift as well as being resistant to antibiotics with time. The outbreak...

Systematic review of sex work interventions in sub-Saharan Africa: Examining combination prevention approaches

2017

OBJECTIVE: The incidence of HIV and sexually transmitted infections is disproportionately high among sex workers (SW). We aimed to update the evidence on the effectiveness of SW interventions in sub-Saharan...

Review: Metabolic syndrome in Black South African women

2017

The prevalence of metabolic syndrome is increasing in African populations, and is particularly high in Black South African women (42%) vs women in the United Kingdom (23%) and the United...

HCV cure and reinfection among people with HIV/HCV coinfection and people who inject drugs

2017

PURPOSE OF REVIEW: Highly effective, well-tolerated interferon-free direct-acting antivirals (DAA) have revolutionised hepatitis C virus (HCV) therapeutics, with the opportunity for broad treatment scale-up among marginalised or “high-risk” populations, including...

Effectiveness of needle and syringe programmes in people who inject drugs – An overview of systematic reviews

2017

BACKGROUND: Needle and syringe programmes (NSP) are a critical component of harm reduction interventions among people who inject drugs (PWID). Our primary objective was to summarize the evidence on the...

Conceptualizing care continua: Lessons from HIV, hepatitis C virus, tuberculosis and implications for the development of improved care and prevention continua

2017

BACKGROUND: To examine the application of continuum models to tuberculosis, HIV, and other conditions; to theorize the concept of continua; and to learn lessons that could inform the development of...

Seroprevalence and diagnosis of HIV, HBV, HCV and syphilis infections among blood donors

2017

BACKGROUND: Blood transfusion is one of the most important therapeutic options of life-saving intervention for recipients who are in diseased or non-diseased conditions with severe blood loss. However, it is...

Incidence of hepatitis C in HIV positive and negative men who have sex with men 2000-2016: A systematic review and meta-analysis

2016

BACKGROUND: There is a need for systematic reviews and meta-analyses to synthesize the epidemiology, and the riskfactors for hepatitis C virus (HCV) among HIV-coinfected and HIV negative men who have...

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