Category Archives: Determinants of Health
Depressive symptoms and its determinants among people living with HIV in Africa: Systematic review and meta-analysis
Background: In Africa, depressive symptoms are prevalent among people living with HIV (PLHIV), significantly impacting their adherence and overall quality of life. The combined burden of HIV and depressive symptoms worsens...
Prevalence and predictors of virological failure among the people living with HIV on antiretroviral treatment in East Africa: Evidence from a systematic review with meta-analysis and meta-regression of published studies from 2016 to 2023
Background: Virological failure (VF) significantly threatens the efficacy of antiretroviral therapy (ART) programs in East Africa. This systematic review and meta-analysis assess the prevalence and predictors of VF among individuals living...
Exploring socio-economic dimensions in HIV research: A comprehensive bibliometric analysis (1992-2024)
The socio-economic burden of HIV infection remains a critical global health concern. This study was conducted to perform a comprehensive bibliometric analysis of the socio-economic burden of HIV infection, highlighting...
The impact of place of residence on antiretroviral therapy adherence: A systematic review and meta-analysis
Objective: There is evidence of geographical variation in HIV coverage and antiretroviral therapy (ART) adherence, and studies have investigated how the place of residence of people living with HIV (PLWH) influences...
Prevalence of late HIV diagnosis and its impact on mortality: A comprehensive systematic review and meta-analysis
Objectives: The late diagnosis of HIV infection plays a crucial role in accelerating the disease progression and increasing the risk of death in the HIV population. However, there remains no consensus...
Leveraging U=U in interventions for Black women living with HIV: A scoping review and call to action
Despite significant reductions in the incidence and prevalence of human immunodeficiency virus (HIV) over recent decades, certain subgroups continue to experience disproportionate HIV-related health disparities. Cisgender Black women, in particular,...
Risk factors associated with human Mpox infection: A systematic review and meta-analysis
BACKGROUND: Mpox emerged as a significant global public health concern during the 2022-2023 outbreak, impacting populations in both endemic and non-endemic countries. This study reviews and synthesises evidence on the...
Chronic kidney disease among people living with HIV on TDF based regimen: A systematic review and meta-analysis
INTRODUCTION: Chronic kidney disease is a major public health concern among people living with human immunodeficiency virus (PLWHIV) who are taking tenofovir disoproxil fumarate-based regimen. Despite the available evidence showing...
The burden of menstrual irregularities among women living with HIV in Nigeria: A comprehensive review
BACKGROUND: Menstrual irregularities significantly distress women living with HIV (WLHIV), impacting their reproductive health and quality of life. Although the underlying mechanism remains inconclusive, studies have outlined possible contributory factors....
Prevalence of mental health problems in people living with HIV: A systematic review and meta-analysis
HIV remains a significant public health concern, with an estimation of 39 million people infected. There is a lack of universally accepted benchmarks for prevalence of mental health problems among...
