Category Archives: Determinants of Health
Pathologising healthy children? A review of the literature exploring the mental health of HIV-affected children in sub-Saharan Africa
This article reviews the expanding body of literature that examines the mental health of HIV-affected children in sub-Saharan Africa. Focusing on primary research across disciplines and methodologies, the review examines...
Antiretroviral pharmacokinetic profile: A review of sex differences
BACKGROUND: Emerging evidence suggests that female sex may be associated with increased risk of developing antiretroviral toxicities. Although the mechanisms of sex-related antiretroviral pharmacodynamic differences remain poorly understood and may...
Association between the CCR2-Val64Ile polymorphism and susceptibility to HIV-1 infection: A meta-analysis
Several studies have investigated whether the CCR2-Val64Ile polymorphism affects susceptibility to human immune deficiency virus type-1 (HIV-1), with inconclusive results. Here, we performed a meta-analysis of the literature aiming to...
A systematic review examining whether interventions are effective in reducing cognitive delay in children infected and affected with HIV
Cognitive delay has been recorded in children infected and affected by HIV. This finding is well established, yet few countries report provision of special educational interventions for this group of...
Racial/ethnic disparities in HIV infection among people who inject drugs: An international systematic review and meta-analysis
AIMS: The Ethnic Minority Meta-Analysis (EMMA) aims to assess racial/ethnic disparities in HIV infection among people who inject drugs (PWID) across various countries. This is the first report of the...
Synthesizing gender based HIV interventions in Sub-Sahara Africa: A systematic review of the evidence
Gender is a critical component of HIV and sexual risk interventions. Examining the range, effectiveness and methodological rigor of studies that include a gender based component can inform current interventions...
Posttraumatic growth and adjustment among individuals with cancer or HIV/AIDS: A meta-analysis
There is increasing research on posttraumatic growth after life-threatening illnesses such as cancer and HIV/AIDS, although it is unclear whether growth confers any psychological or physical benefits in such samples....
Prevalence of bisexual behaviour among bridge population of men who have sex with men in China: A meta-analysis of observational studies
Objective: To integrate the empirical estimates of bisexual behaviour among the bridge population of men who have sex with men (MSM) in China and their HIV and syphilis prevalences stratified...
The impact of HIV treatment on risk behaviour in developing countries: A systematic review
In developing countries, access to antiretroviral therapy (ART) is improving as HIV treatment becomes a greater priority in the global fight against AIDS. While ART has clearly beneficial clinical effects,...
Treatment of syphilis in HIV-infected subjects: A systematic review of the literature
Background: The optimal antimicrobial regimen to treat syphilis in HIV-infected subjects remains controversial. Objective To systematically assess the literature for studies evaluating syphilis treatment regimens in this population. Methods: Two...
