Category Archives: Epidemiology and Determinants of Health

HIV prevalence in primary central nervous system lymphoma: A systematic review and meta-analysis

2020

HIV infection is considered a major risk factor for primary central nervous system lymphoma (PCNSL). However, the percentage of PCNSL that occurs in HIVƒ_%+ƒ_%patients is not well defined. We aimed...

Oral mycobiome identification in atopic dermatitis, leukemia, and HIV patients — A systematic review

2020

INTRODUCTION: Oral mycobiome profiling is important to understand host-pathogen interactions that occur in various diseases. Invasive fungal infections are particularly relevant for patients who have received chemotherapy and for those...

Magnitude of underweight, wasting and stunting among HIV positive children in East Africa: A systematic review and meta-analysis

2020

BACKGROUND: Malnutrition on the background of HIV (Human Immunodeficiency Virus) infection is a complex medical condition that carries significant morbidity and mortality for affected children, with greater mortality from SAM...

Cancer in youth living with HIV (YLWHIV): A narrative review of the access to oncological services among YLWHIV and the role of economic strengthening in child health

2020

Youth Living with HIV/AIDS (YLWHIV) have a higher risk of developing immunodeficiency related illnesses including certain cancers than their general population counterparts of the same age. This narrative review of...

Are Candida albicans isolates from the oral cavity of HIV-infected patients more virulent than from non-HIV-infected patients? Systematic review and meta-analysis

2020

Candida albicans is the main causative agent of oral lesions in HIV-infected patients and its oral colonization is a potential source of systemic dissemination. Although the high prevalence of lesions...

ART uptake and adherence among women who use drugs globally: A scoping review

2020

OBJECTIVE: To assess the state of peer-reviewed literature surrounding uptake and adherence of antiretroviral therapy (ART) among HIV-positive women who use drugs (WWUD). METHODS: Consistent with PRISMA-ScR guidelines, we conducted...

Global prevalence and burden of HIV-associated neurocognitive disorder: A meta-analysis

2020

OBJECTIVES: We aimed to characterise the prevalence and burden of HAND and assess associated factors in the global population with HIV. METHODS: We searched PubMed and Embase for cross-sectional or...

The relationship between potentially traumatic or stressful events, HIV infection and neurocognitive impairment (NCI): A systematic review of observational epidemiological studies

2020

BACKGROUND: HIV/AIDS and potentially traumatic events (PTEs) or stressful life events (SLEs) and/or PTSD are independently associated with neurocognitive impairment (NCI). Literature suggests that HIV and PTE/SLE exposure independently and...

The prevalence of latent and acute toxoplasmosis in HIV-infected pregnant women: A systematic review and meta-analysis

2020

OBJECTIVE: HIV in pregnancy is not only important for mother-to-child HIV transmission, but also it assumes additional importance because HIV increases susceptibility to opportunistic infections, leading to increased morbidity and...

Implications of COVID-19 in high burden countries for HIV/TB: A systematic review of evidence

2020

BACKGROUND: The triple burden of COVID-19, tuberculosis and human immunodeficiency virus is one of the major global health challenges of the twenty-first century. In high burden HIV/TB countries, the spread...

Hepatitis E seroprevalence and viremia rate in immunocompromised patients: A systematic review and meta-analysis

2020

BACKGROUND AND AIMS: Hepatitis E is an infectious disease of the liver caused by the hepatitis E virus (HEV). Immunocompromised patients present a particular risk group, as chronification of hepatitis...

Risk of failure in dual therapy versus triple therapy in naive HIV-patients: A systematic review and meta-analysis

2020

BACKGROUND: Several attempts have been made to test different drug-sparing strategies to reduce the drug-burden and drug-related toxicities. OBJECTIVE: The objective of this meta-analysis was to evaluate the relative risk...

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