Category Archives: Epidemiology and Determinants of Health
Antiretroviral therapy and detection of high-grade cervical intraepithelial neoplasia (CIN2+) at post-CIN management follow-up among women living with HIV: A systematic review and meta-analysis
BACKGROUND: We evaluated the association of antiretroviral therapy (ART), CD4+ count and HIV plasma viral load (PVL) on high-grade cervical intraepithelial neoplasia (CIN2+) detection at follow-up after CIN management among...
Pharmacokinetics, placental and breast milk transfer of antiretroviral drugs in pregnant and lactating women living with HIV
BACKGROUND: Remarkable progress has been achieved in the identification of HIV infection in pregnant women and in the prevention of vertical HIV transmission through maternal antiretroviral treatment (ART) and neonatal...
Risk factors for loss to follow-up from antiretroviral therapy programmes in low- and middle-income countries: A systematic review and meta-analysis
INTRODUCTION: Loss to follow up (LTFU) rates from antiretroviral treatment (ART) programmes in low- and middle-income countries (LMIC) are high, forming an important risk factor for poor treatment outcomes and...
Dental care as a risk factor for transfusion transmissible infections in blood donors: A systematic review and meta-analysis
BACKGROUND AND OBJECTIVES: The deferral policy for blood donation after dental care is based on the precautionary principle. The aim of this systematic review is to give an overview of...
A global meta-analysis of the prevalence of HIV, hepatitis C virus, and hepatitis B virus among people who inject drugs — Do gender-based differences vary by country-level indicators?
BACKGROUND: Women-specific factors exist that increases vulnerability to drug-related harms from injection drug use, including blood-borne viruses (BBVs), but gender-based differences in BBV prevalence have not been systematically examined. METHODS:...
HIV-1 subtype frequency in Northeast Brazil: A systematic review and meta-analysis
Information on human immunodeficiency virus (HIV) molecular epidemiology is required to verify HIV/AIDS (acquired immune deficiency syndrome) epidemic dynamics in different regions, as well as provide support for response to...
Childhood tuberculosis treatment outcome and its association with HIV co-infection in Ethiopia: A systematic review and meta-analysis
Background: Tuberculosis is the second leading cause of death from an infectious disease worldwide, next to HIV. Hence, initiating and determining the national tuberculosis treatment program and outcome is crucial....
A scoping review of interventions to address intimate partner violence in sub-Saharan African healthcare
Intimate partner violence (IPV) is a widespread global health problem, with negative effects on women’s health and HIV transmission and treatment. There is little evidence on how to address IPV...
Community engagement interventions for communicable disease control in low- and lower- middle-income countries: Evidence from a review of systematic reviews
BACKGROUND: Community engagement (CE) interventions include a range of approaches to involve communities in the improvement of their health and wellbeing. Working with communities defined by location or some other...
Socio-demographic and ecological factors associated with anti-HCV prevalence in people who inject drugs: A systematic review
BACKGROUND: The World Health Organization (WHO) aim to eliminate hepatitis C virus (HCV) as a public health threat by 2030. People who inject drugs (PWID) are a key risk group...
Efficacy and safety of direct acting antiviral regimens for hepatitis C virus and human immunodeficiency virus co-infection: Systematic review and network meta-analysis
BACKGROUND AND AIM: Various all-oral direct-acting antiviral (DAA) regimens are being widely used in the treatment of human immunodeficiency virus (HIV)/hepatitis C virus (HCV) co-infected patients; however, the comparative efficacy...
Intimate partner violence (IPV) against HIV-positive women in sub-Saharan Africa: A mixed-method systematic review and meta-analysis
OBJECTIVES: To systematically analyze and summarize the literature on intimate partner violence (IPV) against HIV-positive women in sub-Saharan Africa (SSA) and to identify their risk factors for IPV. METHOD: A...
