Category Archives: Epidemiology and Determinants of Health

Contextual and culturally adapted interventions to improve HIV outcomes: A scoping review

2025

BACKGROUND: Antiretroviral therapy is widely available, yet structural, social, and cultural barriers still limit human immunodeficiency virus prevention and care. Prevention tools such as consistent condom use and pre-exposure prophylaxis...

Viral load suppression after enhanced adherence counseling among HIV patients on antiretroviral therapy (2019–2024): A systematic review and meta-analysis in East Africa

2025

Introduction Viral load suppression is essential for reducing human immunodeficiency virus (HIV) related morbidity and mortality. To eliminate the HIV epidemic and enhance adherence to antiretroviral therapy (ART) globally, the...

Unveiling the underestimated prevalence of HIV, HBV and TB triple infection in Asia, South America, and Africa: A systematic review and meta-analysis

2025

BACKGROUND: Human immunodeficiency virus (HIV) is a genus of retroviruses that targets immune cells and may eventually cause immune-deficiency illness. Triple infection of HIV/hepatitis B virus (HBV) /tuberculosis (TB) leads...

Influences of gender-based stigma on HIV prevention and care among older women: A scoping review

2025

Older women living with HIV are uniquely situated at multiple marginalized intersections because of their gender, age, and HIV status. However, research into how gender-based stigma (GBS) affects HIV prevention...

HIV self-testing and partner notification strategies for key populations in low- to upper-middle-income countries: A mixed-methods systematic review

2025

BACKGROUND: HIV self-testing (HIVST) enhances case diagnosis, but information on its integration for index testing to partner notification is limited. Assessing the acceptability and feasibility of index HIVST and partner...

Burden and challenges of managing hypertension in people living with human immunodeficiency virus (HIV) infection in sub-Saharan African: A mixed systematic review and meta-analysis

2025

Objectives Poor hypertension prevention among people living with HIV (PLHIV) in sub-Saharan Africa may undermine progress in HIV prevention achieved within this population. This review synthesizes data on the prevalence,...

Investigating the influence of provider communication and language reframing on HIV pre-exposure prophylaxis (PrEP) engagement with Black African and Caribbean women: A systematic review

2025

Patient-provider engagement with HIV pre-exposure prophylaxis (PrEP) continues to exhibit significant disparities, particularly among Black African and Caribbean (BAC) women. In the United Kingdom, cisgender women accounted for one-third of...

Global prevalence of HIV and Mycobacterium tuberculosis co-infection: A systematic review and meta-analysis of 371 included articles

2025

OBJECTIVES: Tuberculosis and Human Immunodeficiency Virus (HIV) are two diseases that have imposed the heaviest burden globally. This study aims to determine the global prevalence of Mycobacterium tuberculosis and HIV...

Lessons from the field: A systematic review of global and continental prevalence and challenges of people living with HIV (COVID-19)

2025

COVID-19, caused by SARS-CoV-2, accounts for 186 million infections and more than 4 million deaths globally. This systematic review concentrates on the epidemiological profiling of HIV/AIDS, along with the unique...

Factors associated with unsuppressed HIV viral load among children under 15 years in sub-Saharan africa: A systematic review

2025

BACKGROUND: Viral suppression among children living with HIV remains suboptimal in sub-Saharan Africa. The marked heterogeneity in suppression rates across countries underscores the need for comparative analyses to elucidate context-specific...

Prevalence and determinants of virologic failure among HIV patients on ART in Africa: A systematic review and meta-analysis

2025

Background The Joint United Nations Programme on HIV/AIDS (UNAIDS) has established the 95-95-95 targets, aiming that by 2030, 95% of individuals on ART will achieve viral suppression. While the number...

Global human immunodeficiency virus prevalence and risk behaviors in transmasculine Individuals: A scoping review

2025

PURPOSE: This scoping review sought to synthesize human immunodeficiency virus (HIV) and sexually transmitted infection (STI) prevalence, incidence, risk behaviors, and risk perceptions among transmasculine (TM) individuals globally. METHODS: Eligible...

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