Category Archives: Epidemiology and Determinants of Health
Is the sexual behaviour of young people in sub-Saharan Africa influenced by their peers? A systematic review
Adolescents in sub-Saharan Africa are highly vulnerable to HIV, other sexually transmitted infections (STIs) and unintended pregnancies. Evidence for the effectiveness of individual behaviour change interventions in reducing incidence of...
Epidemiology and impact of HIV coinfection with hepatitis B and hepatitis C viruses in Sub-Saharan Africa
Human immunodeficiency virus (HIV), Hepatitis B (HBV) and Hepatitis C (HCV) are blood-borne viruses with potentially shared routes of transmission. In high-income settings, the impact of antiretroviral therapy (ART) on...
Factors associated with adherence to antiretroviral therapy among adolescents living with HIV/AIDS in low- and middle-income countries: A systematic review
Adolescents living in low- and middle-income countries (LMICs) are disproportionately burdened by the global HIV/AIDS pandemic. Maintaining medication adherence is vital to ensuring that adolescents living with HIV/AIDS receive the...
Systematic review of stigma reducing interventions for African/Black diasporic women
INTRODUCTION: Literature indicates that racism, sexism, homophobia and HIV-related stigma have adverse impacts on health, well-being, and quality of life among HIV-positive women of African descent (African/Black diaspora). However, limited...
TRIM5alpha H43Y polymorphism and susceptibility to HIV-1 infection: A meta-analysis
TRIM5alpha is an antiviral factor that can greatly limit HIV-1 infection. Although several researchers have investigated whether TRIM5alpha H43Y polymorphism influences the risk of HIV-1 infection, no definite conclusion has...
Transactional sex and the HIV epidemic among men who have sex with men (MSM): Results from a systematic review and meta-analysis
Engagement in transactional sex has been hypothesized to increase risk of HIV among MSM, however conflicting evidence exists. We conducted a systematic review and meta-analysis comparing HIV prevalence among MSM...
Behavioral interventions to reduce sexual risk behavior in adults with HIV/AIDS receiving HIV care: A systematic review
Regular interactions with people living with HIV/AIDS (PLWHA) who are receiving care provide caregivers opportunities to deliver interventions to reduce HIV-related risks. We conducted a systematic review of behavioral interventions...
A systematic review and meta-analysis of the prevalence, trends, and geographical distribution of HIV among Chinese female sex workers (2000-2011): Implications for preventing sexually transmitted HIV
OBJECTIVE: The aim of this meta-analysis was to investigate temporal and geographical trends in the HIV epidemic among female sex workers (FSWs) recruited from various venues in China. METHODS: Chinese...
A systematic review of nutritional supplementation in HIV-infected children in resource-limited settings
BACKGROUND: In resource-limited settings, malnutrition is the major cause of death in young children, but the precise benefits of nutritional supplementation for HIV-infected children are not well understood. METHODS: Two...
