Category Archives: Epidemiology and Determinants of Health
Nonoccupational postexposure prophylaxis for human immunodeficiency virus in Sub-Saharan Africa: A systematic review
Both HIV and sexual assault remain major public health problems in Sub-Saharan Africa. This review examines the state of the science regarding provision of non-occupational post-exposure prophylaxis following sexual assault...
The HIV Modes of Transmission model: A systematic review of its findings and adherence to guidelines
INTRODUCTION: The HIV Modes of Transmission (MOT) model estimates the annual fraction of new HIV infections (FNI) acquired by different risk groups. It was designed to guide country-specific HIV prevention...
Non-injection drug use and HIV disease progression in the era of combination antiretroviral therapy
Little is known about the effects of non-injection drug use (NIDU) on HIV antiretroviral treatment outcomes. We conducted a systematic literature search and identified nine publications from prospective cohort studies...
The effects of housing status on health-related outcomes in people living with HIV: A systematic review of the literature
INTRODUCTION: HIV infection is increasingly characterized as a chronic condition that can be managed through adherence to a healthy lifestyle, complex drug regimens, and regular treatment and monitoring. The location,...
Antiretroviral pharmacokinetic profile: A review of sex differences
BACKGROUND: Emerging evidence suggests that female sex may be associated with increased risk of developing antiretroviral toxicities. Although the mechanisms of sex-related antiretroviral pharmacodynamic differences remain poorly understood and may...
Treatment, care and support for people co-infected with HIV and hepatitis C: A scoping review
Background: Providing care for people who are co-infected with both HIV and hepatitis C virus (HCV) is becoming increasingly complex and requires integrated prevention, screening, support and programming efforts. We...
Pathologising healthy children? A review of the literature exploring the mental health of HIV-affected children in sub-Saharan Africa
This article reviews the expanding body of literature that examines the mental health of HIV-affected children in sub-Saharan Africa. Focusing on primary research across disciplines and methodologies, the review examines...
The impact of education on sexual behavior in sub-Saharan Africa: A review of the evidence
Many studies have attempted to determine the relationship between education and HIV status. However, a complete and causal understanding of this relationship requires analysis of its mediating pathways, focusing on...
Reporting of informed consent, standard of care and post-trial obligations in global randomized intervention trials: A systematic survey of registered trials
OBJECTIVE: Ethical guidelines are designed to ensure benefits, protection and respect of participants in clinical research. Clinical trials must now be registered on open-access databases and provide details on ethical...
A systematic review of randomized controlled trials of prenatal and postnatal vitamin A supplementation of HIV-infected women
We searched the Cochrane Library, MEDLINE, EMBASE, AIDSearch, and Gateway to assess the effect of prenatal and/or postnatal vitamin A supplementation on the risk of mother-to-child transmission (MTCT) of HIV...
