Category Archives: Epidemiology and Determinants of Health

Structural racism conceptualization and operationalization for research for the U.S. HIV epidemic: Findings from a scoping review and implications for advancing research for structural interventions

2024

In the U.S., inequities by race/ethnicity in health outcomes, such as in the HIV epidemic, are long standing but have come to the forefront during the COVID-19 pandemic. There is...

Rates of adverse events of antiretroviral therapy in women living with HIV/AIDS: A systematic review and meta-analysis

2024

OBJECTIVE: There is limited information regarding the incidence of treatment-related adverse events (AE) following antiretroviral therapy (ART) in women. So, this review aimed to describe the incidence of AE of...

Incidence density mortality rate among HIV-positive children on antiretroviral therapy in Ethiopia: A systematic review and meta-analysis

2024

BACKGROUND: Human Immunodeficiency Virus (HIV) continues to be the major cause of childhood deaths, particularly in the sub-Saharan African region. In Ethiopia, though several primary studies have been conducted on...

Palliative care considerations for the older adults with HIV/AIDS: A clinical practice review

2024

Human immunodeficiency virus (HIV) has historically been viewed as a terminal condition affecting younger populations, however, with advancements in antiretroviral therapy (ART) and better healthcare provisions, people with HIV are...

Digital technology for HIV self-management in low- and middle-income countries: A scoping review of adolescents’ preferences

2024

Digital health technology interventions have shown promise in enhancing self-management practices among adolescents living with Human Immunodeficiency Virus (ALHIV). The objective of this scoping review was to identify the preferences...

Prevalence, incidence, and case fatality of tuberculous meningitis in adults living with HIV: A systematic review and meta-analysis

2024

BACKGROUND: Tuberculous meningitis (TBM) emerges as a grave complication of tuberculosis in people living with HIV (PLWH). The diagnosis and treatment of TBM pose significant challenges, leading to elevated mortality...

Global epidemiology, natural history, maternal-to-child transmission, and treatment with DAA of pregnant women with HCV: A systematic review and meta-analysis

2024

BACKGROUND: Pregnant Background Pregnant women with hepatitis C virus (HCV) infection represent a special population in which treatment access remains limited despite its increasing prevalence. A reliable estimate of the...

HIV-related stigma and associated factors: A systematic review and meta-analysis

2024

BACKGROUND: It has been recognized that HIV-related stigma hinders efforts in testing, treatment, and prevention. In this systematic review, we aimed to summarize available findings on the association between HIV-related...

Tuberculosis-associated mortality and risk factors for HIV-infected population in Ethiopia: A systematic review and meta-analysis

2024

Background: Despite the effectiveness of antiretroviral therapy in reducing mortality from opportunistic infections among people living with HIV (PLHIV), tuberculosis (TB) continues to be a significant cause of death, accounting...

Burden of multidrug-resistant bacteria among HIV-positive individuals in Ethiopia: A systematic review and meta-analysis

2024

BACKGROUND: Multidrug-resistant (MDR) bacteria are a significant cause of severe infections, particularly in human immunodeficiency virus (HIV)-positive individuals because of their weakened immunity. Since there was no previous pooled representative...

Using mHealth technologies for case finding in tuberculosis and other infectious diseases in Africa: Systematic review

2024

BACKGROUND: Mobile health (mHealth) technologies are increasingly used in contact tracing and case finding, enhancing and replacing traditional methods for managing infectious diseases such as Ebola, tuberculosis, COVID-19, and HIV....

Syndemic theory and its use in developing health interventions and programming: A scoping review

2024

PURPOSE OF REVIEW: The central tenet of syndemics theory is that disease interactions are driven by social factors, and that these factors have to be understood in order to reduce...

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