Category Archives: Epidemiology and Determinants of Health
Redressing the epidemics of opioid overdose and HIV among people who inject drugs in Central Asia: The need for a syndemic approach
BACKGROUND: Accumulating evidence suggests that opioid overdose and HIV infection are burgeoning intertwined epidemics among people who inject drugs (PWID) in Central Asia. To date, however, research on overdose and...
Association between the CCR2-Val64Ile polymorphism and susceptibility to HIV-1 infection: A meta-analysis
Several studies have investigated whether the CCR2-Val64Ile polymorphism affects susceptibility to human immune deficiency virus type-1 (HIV-1), with inconclusive results. Here, we performed a meta-analysis of the literature aiming to...
Factors affecting adherence to short-course ARV prophylaxis for preventing mother-to-child transmission of HIV in sub-Saharan Africa: A review and lessons for future elimination
Despite the biomedical potential to eliminate vertical HIV transmission, drug adherence to short regimens is often sub-optimal. To inform future programmes, we reviewed evidence on the factors influencing maternal and...
The cost-effectiveness of preventing mother-to-child transmission of HIV in low- and middle-income countries: Systematic review
Background: Although highly effective prevention interventions exist, the epidemic of paediatric HIV continues to challenge control efforts in resource-limited settings. We reviewed the cost-effectiveness of interventions to prevent mother-to-child transmission...
Systematic review exploring time trends in the association between educational attainment and risk of HIV infection in sub-Saharan Africa
OBJECTIVE: To assess the evidence that the association between educational attainment and risk of HIV infection is changing over time in sub-Saharan Africa. DESIGN AND METHODS: Systematic review of published...
HIV prevalence amongst injecting drug users in Iran: A systematic review of studies conducted during the decade 1998-2007
Background and objectives: Iran is a country with low HIV prevalence in the general population and concentrated prevalence amongst injecting drug users (IDUs). Various studies have been carried out on...
Stigma in the HIV/AIDS epidemic: A review of the literature and recommendations for the way forward
Although stigma is considered a major barrier to effective responses to the HIV/AIDS epidemic, stigma reduction efforts are relegated to the bottom of AIDS programme priorities. The complexity of HIV/AIDS-related...
Prevalence of bisexual behaviour among bridge population of men who have sex with men in China: A meta-analysis of observational studies
Objective: To integrate the empirical estimates of bisexual behaviour among the bridge population of men who have sex with men (MSM) in China and their HIV and syphilis prevalences stratified...
The impact of different models of specialist palliative care on patients’ quality of life: A systematic literature review
This study set out to systematically review the research evidence about the impact of alternative models of specialist palliative care on the quality of life of patients. Eighty-six relevant papers...
