Category Archives: Epidemiology and Determinants of Health
Acceptability and feasibility of HIV pre-exposure prophylaxis (PrEP) in Southeast Asia: A scoping review
BACKGROUND: The availability of HIV pre-exposure prophylaxis (PrEP) in Southeast Asia remains limited compared to regions like Western Europe or North America. Additionally, little is known about how key populations...
Pre-exposure prophylaxis access, uptake and usage by young people: A systematic review of barriers and facilitators
BACKGROUND: Young people’s sexual health decision-making, including decisions to access and adhere to HIV prevention strategies such as Pre-Exposure Prophylaxis (PrEP), are influenced by a range of internal and external...
Opportunistic infections among schoolchildren who were on antiretroviral therapy in Ethiopia: A systematic review and meta-analysis
INTRODUCTION: The most common and severe cause of morbidity and mortality among HIV- positive children is opportunistic infections (OIs). All HIV-infected children are at risk of developing a variety of...
The impact of the COVID-19 pandemic on HIV healthcare delivery for females in sub-Saharan Africa: A scoping review
Throughout sub-Saharan Africa (SSA), females are disproportionately impacted by HIV and face generalized but also gendered social and economic barriers to accessing HIV healthcare and services. At the outset of...
Gender disparity in health-related quality of life among people living with HIV/AIDS in Ethiopia: A systematic review and meta-analysis
Introduction Health-related quality of life (HRQoL) is a key outcome indicator in antiretroviral therapy program. In Ethiopia, primary studies on gender disparity in HRQoL among people living with HIV/AIDS (PLHA)...
Predictors of maternal HIV acquisition during pregnancy and lactation in sub-Saharan Africa: A systematic review and narrative synthesis
OBJECTIVES: To eliminate vertical transmission of HIV, global institutions recommend using a risk-guided approach for HIV prevention services in antenatal and postnatal settings. Identifying predictors of maternal HIV acquisition can...
Community-based psychosocial support interventions to reduce stigma and improve mental health of people with infectious diseases: A scoping review
BACKGROUND: Stigma experienced by people with infectious diseases impedes access to care, leading to adverse psychosocial consequences. Community-based interventions could prevent or mitigate these consequences but lack robust evidence. This...
Prevalence and associated factors of HIV among female sex workers in Eastern and Southern Africa: Systematic review and meta-analysis
BACKGROUND: Female sex workers (FSWs) are marginalized groups of the population who have limited access to healthcare and a higher risk of HIV infection due to biobehavioral and structural risk...
Adherence to antiretroviral therapy and its associated factors among children living with HIV in Eastern and Southern Africa: A systematic review and meta-analysis
Background: Children living with HIV in low-income settings, such as in Eastern and Southern Africa, are at a high risk for poor adherence to antiretroviral therapy. However, various primary studies presented...
Transitions in treatment: A systematic review and meta-aggregation of preferences and barriers in switching from oral to long-acting injectable antiretroviral therapy among people living with HIV and stakeholders
INTRODUCTION: Antiretroviral treatment (ART) has significantly enhanced health outcomes for people living with HIV (PLWH). With the evolution of treatment options, there is an increasing interest in the development of...
Neuropsychiatric outcomes in children and adolescents with perinatally acquired HIV: A systematic review and meta analysis
Objective: The objective of this study is to define the neuropsychiatric challenges including developmental delay, cognitive impairment, and psychiatric illness faced by children with perinatally acquired HIV. Data sources: Nine databases were...
Application of the COM-B model to facilitators and barriers to HIV and STI testing among people from Black African and Black Caribbean communities in the UK: A scoping review
OBJECTIVE: Individuals from Black African and Black Caribbean communities (black communities) in the UK bear a disproportionate burden of HIV and sexually transmitted infections (STIs), while exhibiting lower testing rates....
