Category Archives: Epidemiology and Determinants of Health

Effectiveness of digital health interventions for improving antiretroviral therapy outcomes in people with HIV: Meta-analysis and trial sequential analysis of randomized controlled trials

2026

Background: Digital health interventions (DHIs) are increasingly used to support antiretroviral therapy (ART) management among people living with HIV. However, existing systematic reviews have largely focused on single intervention types or...

The burden of HIV-related stigma on clinical and quality of life outcomes: results from a systematic literature review

2026

BACKGROUND: HIV-related stigma adversely impacts people with HIV. As part of a systematic literature review (SLR) to evaluate 6 research questions on HIV-related stigma among people with HIV, data from...

Structural competency as a global framework for syndemic HIV care: A critical synthesis

2026

The co-occurrence of HIV with mental health disorders, substance use, and tuberculosis continues to constitute significant global public health issues. Syndemic theory elucidates how these conditions interact synergistically to exacerbate...

Peer-led models for improving HIV treatment and care outcomes among adolescents and young people living with HIV in eastern and southern Africa: A rapid review

2026

Adolescents and Young People Living with HIV have poor levels of adherence to treatment and retention in care. Previous reviews highlighted the need for high-quality evidence on peer-led interventions for...

Prevalence, genetic diversity, and risk factors of cryptosporidium spp. in HIV/AIDS patients: An updated systematic review and meta-analysis (2017–2025)

2026

Background Cryptosporidium spp. is a major opportunistic pathogens in HIV/AIDS patients, contributing substantially to morbidity and mortality worldwide. Despite advances in HIV/AIDS management, the global burden, genetic diversity, and risk factors...

Integrated care models for HIV, diabetes and hypertension in sub-Saharan Africa: A systematic review of effectiveness, implementation and real-world applicability

2026

Background Sub-Saharan Africa faces a syndemic of HIV and non-communicable diseases (NCDs), particularly diabetes and hypertension. Integrated care models have been promoted to improve service efficiency and patient outcomes; however,...

Condom use and associated factors among people living with HIV/AIDS on anti-retroviral therapy (ART) in Ethiopia: A systematic review and meta-analysis

2026

Condom use remains a crucial preventive measure for individuals undergoing antiretroviral therapy (ART) in the fight against HIV/AIDS. This review and meta-analysis aimed to determine the pooled prevalence of condom...

Area-based measures of socioeconomic status in studies assessing health outcomes among people living with HIV in Canada and the USA: A scoping review

2026

OBJECTIVE: Area-based measures of socioeconomic status (SES) are increasingly used to study health disparities among people living with HIV (PLWH), with wide variation in how they are defined and applied...

Socio-cultural and systematic factors influencing fertility desire among women living with HIV: A systematic literature review

2026

Women and girls in Sub-Saharan Africa remain disproportionately affected by HIV. HIV care strategies can significantly reduce the risk of mother-to-child transmission of HIV. Women living with HIV (WLHIV) often...

Prevalence of left ventricular systolic dysfunction in HIV-infected children from sub-Saharan Africa: A systematic review and meta-analysis

2026

Background Left ventricular systolic dysfunction (LVSD) is an emerging non-communicable complication among children living with Human Immunodeficiency Virus (HIV), particularly in Sub-Saharan Africa, where paediatric HIV burden remains high. However,...

Exclusive breastfeeding and associated factors among HIV-infected mothers in sub-Saharan African countries: A systematic review and meta-analysis

2026

Introduction The World Health Organization recommends exclusive breastfeeding for the first six months, along with maternal antiretroviral treatment, to reduce the risk of HIV transmission to infants and promote their...

Assessing the state of published HIV research concerning sexual minority women: A global English language scoping review

2026

PURPOSE: We conducted a scoping review to map peer-reviewed literature on HIV research concerning sexual minority women (SMW). METHODS: Following guidance from Arksey and O’Malley’s framework and the Preferred Reporting...

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