Category Archives: Epidemiology and Determinants of Health

Virologic suppression among HIV-positive pregnant and lactating women receiving antiretroviral therapy in Africa: A systematic review and meta-analysis

2026

Background The elimination of mother-to-child transmission of human immunodeficiency virus (HIV) is a key global public health priority. In Africa, virologic failure among people living with HIV continues to pose a...

HIV in Iraq: Key populations, sociodemographics, transmission modes, present realities, and urgent next steps: A systematic review

2026

Background and Purpose While empirical studies in Iraq have examined sociodemographic characteristics and modes of human immunodeficiency virus (HIV) transmission, including but not limited to those involving key populations, there...

Effect of BMI on mortality in patients with tuberculosis and HIV coinfection in Asia and Africa: Systematic review and meta-analysis

2026

Background Tuberculosis (TB) continues to pose a major global health threat, particularly in low- and middle-income countries. An estimated 10.8 million people developed TB in 2023, corresponding to 134 cases...

Peer network approaches for improving HIV testing, prevention and care utilisation among men in sub-Saharan Africa: A scoping review

2026

INTRODUCTION: Limited male engagement in HIV prevention and care is a global challenge more pronounced in sub-Saharan Africa (SSA) contributing to ongoing transmission. However, peer network interventions show promise in...

Risk factors and mortality rates for children co-infected with HIV and TB in Ethiopia: A systematic review and meta-analysis

2025

This systematic review and meta-analysis aimed to identify risk factors and mortality rates in HIV and TB co-infected children in Ethiopia. An electronic literature search was conducted using multiple databases,...

Risk factors for HIV-associated neurocognitive impairment and frailty in aging people with HIV in Latin America: A systematic review

2026

Background As people living with HIV (PWH) in Latin America and the Caribbean (LAC) have longer life expectancy due to improved access to antiretroviral therapy (ART), complications such as HIV-associated...

Effects of digital health interventions to promote safer sex behaviors among youth: Systematic review and Bayesian network meta-analysis

2026

Background Youth aged 15–24 years carry a disproportionate HIV/sexually transmitted infections (STIs) burden. In recent years, different modalities of digital health interventions (DHIs) have been explored to promote safer sex behaviors...

Age-specific distribution of cervical precancer and cancer among women living with HIV across seven countries: A systematic review and an individual patient data meta-analysis

2026

Background Women living with HIV have an elevated risk for cervical cancer, present earlier, and have more recurrent human papillomavirus (HPV) infections compared with women without HIV. To update WHO recommendations...

Colliding wars: A systematic review on HIV responses in conflict-affected settings

2026

BACKGROUND: Armed conflicts are an escalating threat to public health, often marked by violence, poverty, displacement and weakened health systems-conditions that mirror the drivers of HIV transmission. AIM: This review...

Perceptions about the relationship between HIV, antiretroviral therapy (ART), and fecundity in sub-Saharan Africa: Findings from a systematic scoping review

2026

Advances in antiretroviral therapy (ART) enable women living with HIV to safely conceive and give birth without vertical transmission. However, in sub-Saharan Africa, 1 in 6 people experience infertility and...

Polypharmacy in HIV: Rethinking what counts and why it matters

2025

Polypharmacy, the concurrent use of multiple medications, presents a growing challenge in HIV care as people living with HIV age and experience earlier onset of age-related co-morbidities. However, how polypharmacy...

HIV and cardiovascular diseases: A systematic review and comparative risk assessment study

2026

Background People living with HIV (PLWH) face a significantly elevated risk of cardiovascular diseases (CVDs). This study aims to quantify temporal trends in HIV-attributable CVD burden at global, regional and...

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