Category Archives: Epidemiology and Determinants of Health

Assessing the impact, barriers and facilitators of peer-driven interventions on the prevention of mother-to-child transmission of HIV in low- and middle-income countries: A systematic review and meta-analysis

2026

Introduction: Peer interventions may improve retention across the prevention of mother-to-child transmission (PMTCT) cascade in low- and middle-income countries (LMICs), where poor adherence to antiretroviral therapy (ART) remains a major barrier....

Breastfeeding practices and perspectives in the setting of maternal HIV in high-income countries since the shift in the United States national guidelines: A scoping review

2026

Introduction: United States national guidelines around infant feeding in the setting of maternal HIV were updated significantly in 2023. The updated guidelines encourage evidence-based counseling and emphasize shared decision-making around infant...

The role of subtyping methodologies in HIV surveillance and vaccine development: A systematic review and meta-analysis

2026

BACKGROUND: HIV genetic diversity has increased over time, with recombinant forms becoming more prevalent and complicating subtype classification and surveillance, particularly in low-and-middle income countries (LMICs). Accurate subtyping is critical...

The role of religion and spirituality in HIV prevention: A systematic literature review and network analysis

2026

Religion and spirituality play an important role in shaping attitudes, beliefs, social norms, and preventive behaviors related to Human Immunodeficiency Virus (HIV) prevention across diverse populations and cultural settings. This...

Mapping psychosocial interventions for mental health and well-being among pregnant women living with HIV: A scoping review

2026

BACKGROUND: Pregnant women living with HIV are at increased risk of depression, anxiety, stigma, gender-based violence, and poor engagement in prevention of mother-to-child transmission services. Psychosocial interventions are increasingly used...

Housing instability as a barrier to HIV viral suppression: Evidence from a U.S. systematic review and meta-analysis

2026

Housing instability and homelessness remain pervasive structural determinants of poor HIV outcomes in the United States. People living with HIV (PLWH) who experience homelessness face intersecting barriers, including stigma, behavioral...

Global prevalence and biopsychosocial correlates of psychological distress among people living with HIV: An updated theory-informed meta-analysis

2026

Introduction:  Psychological distress (PD) is common among people living with HIV (PLWH), but prevalence estimates vary substantially. This study aimed to synthesize the prevalence of PD among PLWH and examine...

Organization and integration of care in the HIV-non-communicable disease syndemic: A rapid scoping review

2026

Advances in antiretroviral therapy have transformed infection with HIV into a manageable chronic disease, increasing the survival of people living with HIV, who are also undergoing a demographic aging process...

Global mental health disparities among transgender women and transfeminine people living with HIV: A systematic review and meta-analysis of 63 studies

2026

Background Transgender women and transfeminine people face a disproportionate burden of mental health conditions driven by stigma, discrimination, and structural inequities, with additional psychosocial challenges related to HIV diagnosis and...

Incidence of occupational HIV seroconversion among healthcare workers: A systematic review and meta-analysis

2026

Background Healthcare workers (HCWs) may be at elevated risk of HIV infection due to the global HIV burden and frequent occupational exposure to blood and body fluids (BBF). This systematic...

Prevalence of HIV and hepatitis B co-infection in Nigeria: A systematic review and meta-analysis

2026

Introduction Hepatitis B virus (HBV) and Human Immunodeficiency virus (HIV) infections are both major public health concerns in sub-Saharan Africa. Co-infection with these virus accelerates liver disease progression, increases hepatotoxicity,...

A systematic review of obstetric mistreatment among women living with HIV

2026

Several studies have established that women living with HIV frequently encounter mistreatment when accessing maternal healthcare. Previous reviews on obstetric mistreatment have largely focused on the general population, leaving an...

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