Category Archives: Epidemiology and Determinants of Health

Risk factors for HIV-associated neurocognitive impairment and frailty in aging people with HIV in Latin America: A systematic review

2026

Background As people living with HIV (PWH) in Latin America and the Caribbean (LAC) have longer life expectancy due to improved access to antiretroviral therapy (ART), complications such as HIV-associated...

Effects of digital health interventions to promote safer sex behaviors among youth: Systematic review and Bayesian network meta-analysis

2026

Background Youth aged 15–24 years carry a disproportionate HIV/sexually transmitted infections (STIs) burden. In recent years, different modalities of digital health interventions (DHIs) have been explored to promote safer sex behaviors...

Age-specific distribution of cervical precancer and cancer among women living with HIV across seven countries: A systematic review and an individual patient data meta-analysis

2026

Background Women living with HIV have an elevated risk for cervical cancer, present earlier, and have more recurrent human papillomavirus (HPV) infections compared with women without HIV. To update WHO recommendations...

Colliding wars: A systematic review on HIV responses in conflict-affected settings

2026

BACKGROUND: Armed conflicts are an escalating threat to public health, often marked by violence, poverty, displacement and weakened health systems-conditions that mirror the drivers of HIV transmission. AIM: This review...

Perceptions about the relationship between HIV, antiretroviral therapy (ART), and fecundity in sub-Saharan Africa: Findings from a systematic scoping review

2026

Advances in antiretroviral therapy (ART) enable women living with HIV to safely conceive and give birth without vertical transmission. However, in sub-Saharan Africa, 1 in 6 people experience infertility and...

Polypharmacy in HIV: Rethinking what counts and why it matters

2025

Polypharmacy, the concurrent use of multiple medications, presents a growing challenge in HIV care as people living with HIV age and experience earlier onset of age-related co-morbidities. However, how polypharmacy...

HIV and cardiovascular diseases: A systematic review and comparative risk assessment study

2026

Background People living with HIV (PLWH) face a significantly elevated risk of cardiovascular diseases (CVDs). This study aims to quantify temporal trends in HIV-attributable CVD burden at global, regional and...

Incidence and predictors of opportunistic infection among people living with HIV in Ethiopia: A systematic review and meta-analysis

2026

Background Opportunistic infections (OIs) play a crucial role in the morbidity and mortality of HIV‐infected individuals. Despite the increasing use of antiretroviral therapy, there remains a lack of comprehensive data...

Mental health of women with HIV: A qualitative meta-synthesis

2026

BACKGROUND: Women living with human immunodeficiency virus (HIV) experience significant psychological burdens due to biological and gendered factors such as pregnancy, childbirth and breastfeeding. However, a life course-based understanding of...

HIV prevention interventions for men who have sex with men

2026

Key take-home messages

Cancer in older adults living with HIV

2026

Key take-home messages

Models of primary health care for people living with HIV

2026

Key take-home messages

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