Category Archives: Epidemiology and Determinants of Health
Post-exposure prophylaxis against blood-borne viral infections among health care workers: A bibliometric analysis
Background: Health care workers face a wide range of chemical, physical, and biological occupational hazards in their jobs. Objective: The present study aimed to investigate research trends on post-exposure prophylaxis (PEP) against...
Systematic review and meta-analysis of linkage to HIV care interventions in the United States, Canada, and Ukraine (2010–2021)
We conducted a systematic review and meta-analysis of interventions targeting linkage to HIV care in the US, Canada, and Europe. We searched six databases (PubMed, Embase, Cochrane Library, Web of...
Oral hyperpigmentation as an adverse effect of highly active antiretroviral therapy in HIV patients: A systematic review and pooled prevalence
Background: Human Immunodeficiency Virus (HIV) infects patients via CD4+ cells which are later be destroyed subsequently causing the deteriotation of immune system. HIV generally manifests in the oral cavity as the...
Safety and efficacy of long-acting injectable agents for HIV-1: Systematic review and meta-analysis
Background: HIV-1 infection continues to affect global health. Although antiretrovirals can reduce the viral load or prevent HIV-1 infection, current drugs require daily oral use with a high adherence level. Long-acting...
A systematic review and meta-analysis of the prevalence of triplex infections (combined Human Immunodeficiency Virus, hepatitis B Virus, and hepatitis C Virus) among pregnant women in Nigeria
OBJECTIVE: We systematically identified the prevalence of triplex infections (combined human immunodeficiency virus (HIV), hepatitis B virus (HBV), and hepatitis C virus (HCV)) in pregnancy. METHODS: To gather information on...
Virtual avatars as a new tool for human immunodeficiency virus prevention among men who have sex with men: A narrative review
BACKGROUND AND OBJECTIVE: Human immunodeficiency virus (HIV) continues to affect sexual and gender minorities, predominantly men who have sex with men (MSM). Stigma, medical mistrust, and apprehension towards discussing sexual...
Adverse perinatal outcomes attributable to HIV in sub-Saharan Africa from 1990 to 2020: Systematic review and meta-analyses
Background: Maternal HIV infection and antiretroviral drugs (ARVs) are associated with increased risks of adverse perinatal outcomes. The vast majority of pregnant women living with HIV (WLHIV) reside in sub-Saharan Africa....
Global and regional estimate of HIV-associated stroke burden: A meta-analysis and population attributable modeling study
Background: This study aimed to determine the correlation between human-immunodeficiency-virus (HIV) infection and stroke, as well as to estimate the global, regional, and national burden of HIV-associated stroke. Methods: A registered meta-analysis...
Association between integrase strand transfer inhibitor use with insulin resistance and incident diabetes mellitus in persons living with HIV: A systematic review and meta-analysis
Whether integrase strand transfer inhibitors (INSTIs) are associated with a higher risk of incident type 2 diabetes mellitus (DM) than other antiretroviral therapies (ART) needs to be established. MEDLINE, Embase,...
Pharmacotherapeutic interventions in people living with HIV undergoing solid organ transplantation: A scoping review
The pharmacotherapeutic management of people living with HIV (PLWHIV) undergoing solid organ transplantation (SOT) is clinically challenging, mainly due to the frequent occurrence of complex drug-drug interactions. Although various strategies...
