Category Archives: Epidemiology and Determinants of Health
Global associations of key populations with HIV-1 recombinants: A systematic review, global survey, and individual participant data meta-analysis
INTRODUCTION: Global HIV infections due to HIV-1 recombinants are increasing and impede prevention and treatment efforts. Key populations suffer most new HIV infections, but their role in the spread of...
Geographic and population distributions of HIV-1 and HIV-2 circulating subtypes: A systematic literature review and meta-analysis (2010–2021)
BACKGROUND: HIV continues to be a major source of morbidity and mortality. Among the main challenges faced by prophylactic HIV vaccine development are the high rates of genetic mutation and...
Incidence and prevalence of hepatitis C virus among HIV-negative gay and bisexual men using HIV pre-exposure prophylaxis (PrEP): A systematic review and meta-analysis
BACKGROUND: Gay and bisexual men using HIV pre-exposure prophylaxis (PrEP) are at increased risk for sexually transmissible infections. Hepatitis C virus (HCV) risk among PrEP users is less clear. We...
A systematic review of intervention studies that address HIV-related stigmas among US healthcare workers and health systems: Applying a theory-based ontology to link intervention types, techniques, and mechanisms of action to Potential Effectiveness
BACKGROUND: To end the HIV epidemic, we need to better understand how to address HIV-related stigmas in healthcare settings, specifically the common theoretical bases across interventions so that we can...
Integrated health care delivery for adolescents living with and at risk of HIV infection: A review of models and actions for implementation
Integrated service delivery, providing coordinated services in a convenient manner, is important in HIV prevention and treatment for adolescents as they have interconnected health care needs related to HIV care,...
Reactivation rates of hepatitis B or C or HIV in patients with psoriasis using biological therapies: A systematic review and meta-analysis
Some biological therapiSome biological therapies for psoriasis can cause the reactivation of viral infections. Although recent studies suggest no increased rate of reactivation with biological therapies, some life-threatening cases have...
Adverse impact of intimate partner violence against HIV-positive women during pregnancy and post-partum: Results from a meta-analysis of observational studies
Objectives: Intimate partner violence (IPV) against pregnant or human immunodeficiency virus (HIV)-positive women have been previously studied. However, data on the impact of IPV on HIV-positive pregnant women have not...
The association between HIV diagnosis disclosure and adherence to anti-retroviral therapy among adolescents living with HIV in Sub-Saharan Africa: A systematic review and meta-analysis
INTRODUCTION: Nine in ten of the world’s 1.74 million adolescents living with human immunodeficiency virus (ALHIV) live in Sub-Saharan Africa. Suboptimal adherence to antiretroviral therapy (ART) and poor viral suppression...
Microbiological study of periodontal disease in populations with HIV: A systematic review and meta-analysis
BACKGROUND: No systematic review/meta-analysis has been conducted on the microbiological profile associated with the occurrence of periodontitis in patients with HIV. The aim of this study was to evaluate the...
Treatment failure and associated factors among people living with HIV on highly active antiretroviral therapy in mainland China: A systematic review and meta-analysis
Objective: Reducing the prevalence of treatment failure among people living with HIV (PLHIV) on highly active antiretroviral therapy (HAART) is crucial for improving individual health and reducing disease burden. This study...
Maternal antiretroviral treatment for HIV infection and risk of small-for-gestational-age birth: A systematic review and meta-analysis of protease inhibitor-based treatment and timing of treatment
Background: Data indicate that certain combination antiretroviral treatment (cART) regimens, particularly protease inhibitor (PI)-based regimens, and cART initiation before conception may be associated with adverse pregnancy outcomes. The risk of having...
