Category Archives: Epidemiology and Determinants of Health
A systematic review exploring racial disparities, social determinants of health, and sexually transmitted infections in Black women
OBJECTIVE: To explore and describe racial disparities, the role of social determinants of health, and individual risk behaviors among Black women as related to sexual health and/or sexually transmitted infections...
Diagnostic accuracy of the interferon-gamma release assay in acquired immunodeficiency syndrome patients with suspected tuberculosis infection: A meta-analysis
PURPOSE: The diagnostic accuracy of the interferon-gamma release assay (IGRA) in immunosuppressed patients remains unclear. METHODS: A systematic review and meta-analysis were performed for diagnostic test accuracy of IGRA in...
Discontinuation, suboptimal adherence, and reinitiation of oral HIV pre-exposure prophylaxis: A global systematic review and meta-analysis
Background: Poor adherence to oral HIV pre-exposure prophylaxis (PrEP) diminishes its clinical and public health benefits. This study synthesises evidence regarding discontinuation, adherence, and reinitiation of PrEP among geographically diverse PrEP...
Effects of different integrase strand transfer inhibitors on body weight in patients with HIV/AIDS: A network meta-analysis
Background: Global antiretroviral therapy has entered a new era. Integrase strand transfer inhibitor (INSTI) has become the first choice in acquired immunodeficiency syndrome (AIDS) treatment. Because INSTI has high antiviral efficacy,...
Effects of interleukin-10 -1082G/A and -592C/A gene polymorphisms on the risk of human immunodeficiency virus-1 infection: An updated meta-analysis
This paper has aimed to review the available evidence on the association between Interleukin (IL) -10 -1082G/A, -592C/A gene polymorphisms and the risk of human immunodeficiency virus-1(HIV-1) infection. The data...
Magnitude and associated factors of urinary tract infections among adults living with HIV in Ethiopia—Systematic review and meta-analysis
BACKGROUND: Urinary tract infection is a major public health problem in developing countries among immunocompromized populations where there are limited health-care services. People living with human immunodeficiency virus (HIV) are...
The impact of genital ulcers on HIV transmission has been underestimated—A critical review
In the early 1990s, several observational studies determined that genital ulcer disease (GUD), in either the index or the exposed person, facilitates HIV transmission. Several meta-analyses have since presented associated...
Interventions to improve early retention of patients in antiretroviral therapy programmes in sub-Saharan Africa: A systematic review
BACKGROUND: Several interventions to improve long term retention (12 months and above) on treatment have been rigorously evaluated in Sub-Saharan Africa (SSA). However, research on interventions to improve retention of...
The association between methamphetamine use and number of sexual partners in men who have sex with men: A systematic review and meta-analysis
BACKGROUND: Methamphetamine use in men who have sex with men population is significantly higher than that in the general population. Meth use can cause high-risk sexual behaviors, such as having...
Use of HIV recency assays for HIV incidence estimation and other surveillance use cases: Systematic review
BACKGROUND: HIV assays designed to detect recent infection, also known as “recency assays,” are often used to estimate HIV incidence in a specific country, region, or subpopulation, alone or as...
Men missing from the HIV care continuum in sub-Saharan Africa: A meta-analysis and meta-synthesis
Introduction: Men are missing along the HIV care continuum. However, the estimated proportions of men in sub-Saharan Africa meeting the UNAIDS 95-95-95 goals vary substantially between studies. We sought to estimate...
Impact of supervised aerobic exercise on clinical physiological and mental parameters of people living with HIV: A systematic review and meta-analyses of randomized controlled trials
Background: The benefits derived from supervised aerobic exercise in people living with human immunofeficiency virus- HIV (PLWH) have not yet been clearly identified.Objective: To evaluate the impact of supervised aerobic exercise on...
