Category Archives: Epidemiology and Determinants of Health
Interventions to increase the uptake and continuation of pre-exposure prophylaxis (PrEP) by adolescent girls and young women at high risk of HIV in low-income and middle-income countries: A scoping review
INTRODUCTION: Effective strategies to increase pre-exposure prophylaxis (PrEP) uptake and continuation among adolescent girls and young women (AGYW) who engage in sex work or transactional sex are sparsely reported. We...
Integrating pre-exposure prophylaxis of HIV infection into family planning services: A scoping review
INTRODUCTION: The aim of this review was to map evidence of integrating pre-exposure prophylaxis (PrEP) for HIV prevention into family planning services. A comprehensive package, using a combination of PrEP...
Web-based service provision of HIV, viral hepatitis, and sexually transmitted infection prevention, testing, linkage, and treatment for key populations: Systematic review and meta-analysis
BACKGROUND: Despite the growth of web-based interventions for HIV, viral hepatitis (VH), and sexually transmitted infections (STIs) for key populations, the evidence for the effectiveness of these interventions has not...
The prevalence of HIV infection in minority Indigenous populations of the South-East Asia and Western Pacific regions: A systematic review and meta-analysis
A random effects meta-analysis was used to estimate the pooled prevalence of HIV infection within minority indigenous populations of the South-East Asia (SEAR) and Western Pacific Regions (WPR). Sub-group analyses...
Virological failure and adherence to antiretroviral therapy in adolescents and young adults living with human immunodeficiency virus
Objective: HIV (human immunodeficiency virus) infection remains a major public health challenge. Infected young people at any age are less likely to adhere to care in a timely manner and to...
Prevalence and characteristics of nonalcoholic fatty liver disease and fibrosis in people living with HIV monoinfection: A systematic review and meta-analysis
Background and Aims Liver disease remains a leading cause of morbidity and mortality among people living with HIV (PLWH). Emerging data have shown that PLWH are at high risk for...
The prevalence of HIV-infected patients with virological suppression but a CD4+ T-cell count of ≤ 200 cells/mm3 after highly active antiretroviral therapy initiation: A meta-analysis
Highly active antiretroviral therapy (HAART) strongly inhibits HIV replication. However, many patients show suboptimal immune recovery (SIR), as defined by virological suppression (i.e. low viral load) with a CD4+ T-cell count...
A systematic review and meta-analysis to estimate the time from HIV infection to diagnosis for people with HIV
Timely HIV diagnosis is critical to minimizing transmission events. We sought to estimate the meantime from HIV infection to diagnosis and its temporal trend among people with HIV. Following Preferred...
So many harms, so little benefit: A global review of the history and harms of HIV criminalisation
Since the early years of HIV, many jurisdictions have criminalised HIV non-disclosure, potential or perceived exposure, and transmission. Many of these laws and prosecutions are without a scientific basis and...
Perinatal outcomes associated with combination antiretroviral therapy compared with monotherapy
Objectives: Increasing numbers of women living with HIV (WLHIV) worldwide receive combination antiretroviral therapy (cART) during pregnancy. We aimed to assess the risk of adverse perinatal outcomes in pregnant WLHIV receiving...
Toxoplasma gondii infection in immunocompromised patients in Iran (2013–2022): A systematic review and meta-analysis
BACKGROUND: Toxoplasma gondii infection (toxoplasmosis) has the potential to cause a serious disease in immunocompromised patients and can be fatal in this population. We conducted a systematic review and meta-analysis...
Determining the screening frequency for sexually transmitted infections for people who use HIV pre-exposure prophylaxis: A systematic review and meta-analysis
Background: Although the World Health Organization (WHO) recommends ‘frequent’ screening of sexually transmitted infections (STI) for people who use pre-exposure prophylaxis (PrEP) for HIV, there is no evidence for optimal frequency....
