Category Archives: Epidemiology and Determinants of Health

Safety and efficacy of abacavir for treating infants, children, and adolescents living with HIV: A systematic review and meta-analysis

2022

Background: Abacavir is a nucleoside reverse transcriptase inhibitor recommended in paediatric HIV care. We assessed the safety and efficacy profile of abacavir used in first, second, or subsequent lines of treatment...

Adherence to option B+ and its association with disclosure status and counseling among HIV-positive pregnant and lactating women in Ethiopia: Systematic review and meta-analysis

2022

Objectives: This systematic review and meta-analysis aimed to assess the pooled estimate of option B+ level of adherence and its association with disclosure status and counseling among pregnant and lactation women...

Increased risk of sexually transmitted infections in men who have sex with men taking preexposure prophylaxis: A meta-analysis

2022

BACKGROUND: Men who have sex with men (MSM) are a priority population for preexposure prophylaxis (PrEP) for HIV prevention. We summarized the surveillance data from the studies of MSM taking...

Prevalence and global trends of polypharmacy among people living with HIV: A systematic review and meta-analysis

2022

Background: There has been a rising prevalence of polypharmacy among people living with HIV (PLWH). Uncertainty however remains regarding the exact estimates of polypharmacy among these cohorts of patients. Methods: We conducted...

The clinical effect of point-of-care HIV diagnosis in infants: A systematic review and meta-analysis

2022

Background: Timely diagnosis and treatment of HIV is crucial in HIV-exposed infants to prevent the high rates of mortality seen during the first 2 years of life if HIV is untreated....

The global burden of cognitive impairment in people living with HIV: A systematic review and meta-analysis

2022

Objective: While life expectancies of people with HIV (PWH) have increased through the successes of antiretroviral treatment, cognitive impairment remains a pressing concern. Prevalence estimates vary worldwide as different definitions for...

When law and science part ways: the criminalization of breastfeeding by women living with HIV

2022

Stigma and discrimination are a constant reality for the 37.7 million people living with human immunodeficiency virus (HIV) around the globe. Fear over vertical transmission has fuelled HIV criminalization: laws...

Malaria prevalence in HIV-positive children, pregnant women, and adults: A systematic review and meta-analysis

2022

Background: Malaria in human immunodeficiency virus (HIV)-positive patients is an ever-increasing global burden for human health. The present meta-analysis summarizes published literature on the prevalence of malaria infection in HIV-positive children,...

Barriers to accessing pre-exposure prophylaxis among women experiencing intimate partner violence in the United States: A systematic literature review

2022

Women experiencing intimate partner violence (IPV) are at increased risk of human immunodeficiency virus (HIV) infection but have limited uptake of pre-exposure prophylaxis (PrEP). We systematically reviewed the existing evidence...

Association of HIV infection with cardiovascular pathology based on advanced cardiovascular imaging: A systematic review

2022

Importance: HIV-associated cardiovascular disease is increasing in prevalence, but its mechanisms remain poorly understood. Objective: To systematically review data from advanced cardiovascular imaging studies evaluating computed tomographic coronary angiography, positron emission tomography...

What is the global prevalence of depression among men who have sex with men? A systematic review and meta-analysis

2022

Background: Depression due to stigma resulting from their sexual identity, isolation, social exclusion, and insufficient access to care and counseling services has become a health problem among men who have sex...

Does sickle cell disease protect against HIV infection: A systematic review

2022

OBJECTIVE: The aim of this systematic review was to investigate if SCD protects against HIV infection by determining the association between SCD and the incidence and virulence of HIV infection....

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