Category Archives: Mental Health

Multimodal approach to neurocognitive function in people living with HIV in the cART era: A comprehensive review

2024

Combination antiretroviral treatment (cART) has revolutionized the management of human immunodeficiency virus (HIV) and has markedly improved the disease burden and life expectancy of people living with HIV. HIV enters...

The intersection of mental health and sexual and gender minority identities for older adults living with Human Immunodeficiency Virus: A narrative review

2024

The transition of HIV into a chronic illness has brought to the forefront the pressing need to address the complex web of social determinants of HIV outcomes. A structured literature...

Molecular role of HIV-1 human receptors (CCL5-CCR5 Axis) in neuroAIDS: A systematic review

2024

Chronic HIV-1 infection can cause neurological illness, also known as HIV-associated neurocognitive disorders (HAND). The elevated level of pro-inflammatory cytokines and chemokines, such as C-C Chemokine Ligand 5 (CCL5/RANTES), is...

HIV associated neurocognitive disorder screening and diagnosis pathways in Australia: A scoping review and international implications

2024

Symptomatic HIV-associated neurocognitive disorder (HAND) is a complication of HIV (cognitive impairment, difficulties with everyday functioning). If detected early, interventions assist with optimizing care, avoiding rapid decline and enhancing coping....

Transactivator of transcription (Tat)-induced neuroinflammation as a key pathway in neuronal dysfunction: A scoping review

2024

The activity of HIV-1 and its viral proteins within the central nervous system (CNS) is responsible for a wide array of neuropathological effects, resulting in a spectrum of neurocognitive deficits...

Psychoeducational interventions for people living with chronic communicable disease: A systematic review

2024

OBJECTIVE: Psychoeducation is increasingly recognised for its value in facilitating adaption to a chronic disease diagnosis. This study aimed to synthesise available literature on the psychoeducation interventions available to adults...

Suicidal ideation, attempt, and its associated factors among adult HIV/AIDS patients in Ethiopia: A systematic review and meta-analysis study

2024

BACKGROUND: WHO statistics show that someone attempts suicide every three seconds and commits suicide every 40 seconds somewhere in the world. There is a scarcity of aggregate evidence in Ethiopia....

Psychosocial distress among young men who have sex with men: A scoping review

2024

PURPOSE: Psychosocial distress negatively impacts coping and adaptation among young men (aged 18 to 44 years) who have sex with men (YMSM) with, or at risk of acquiring, HIV. However,...

People who living with HIV/AIDS also have a high prevalence of anxiety disorders: A systematic review and meta-analysis

2024

BACKGROUND: An estimated 301 million people worldwide suffer from anxiety disorders. People living with HIV/AIDS (PLWHA) are particularly prone to anxiety disorders that could interfere with the important developmental process...

Mental health burden among females living with HIV and AIDS in sub-Saharan Africa: A systematic review

2024

Mental health problems, particularly depression and anxiety, are common in women and young girls living with HIV/ AIDS particularly in low- and middle-income (LMICs) countries where women’s vulnerability to psychiatric...

Global prevalence of depressive symptoms among people living with HIV/AIDS: A systematic review and meta-analysis of the past five years

2024

A clear and accurate assessment of depressive symptoms among people living with HIV/AIDS (PLWHA) in the past five years is essential to help develop reasonable and sound interventions to improve...

Recent advances in HIV-associated neurocognitive disorders: A focus on older adults and sub-Saharan Africa

2024

PURPOSE OF REVIEW: We reviewed recent literature on prevalence and interventional approaches for cognitive impairment in the context of HIV infection alongside current controversies and challenges around its nomenclature, screening,...

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