Category Archives: Depression
Drug-drug interactions with antiviral agents in people who inject drugs (PWID) requiring substitution therapy
OBJECTIVE: To describe potential drug-drug interactions in the area of HIV/hepatitis C virus (HCV) coinfection and injection drug use, including those between antiretrovirals (ARVs), direct-acting antivirals (DAAs), and opioid-agonist therapy,...
Syndemics of psychosocial problems and HIV risk: A systematic review of empirical tests of the disease interaction concept
In the theory of syndemics, diseases co-occur in particular temporal or geographical contexts due to harmful social conditions (disease concentration) and interact at the level of populations and individuals, with...
Psychological interventions for common mental disorders for people living with HIV in low- and middle-income countries: Systematic review
OBJECTIVE: To assess the effectiveness of structured psychological interventions against common mental disorders (CMD) in people living with HIV infection (PLWH), in low- and middle-income countries (LMIC). METHODS: Systematic review...
Depression and adherence to antiretroviral therapy in low-, middle- and high-income countries: A systematic review and meta-analysis
We investigated the associations between depressive symptoms and adherence to antiretroviral therapy (ART) among people living with HIV (PLHIV). We searched the PubMed, EMBASE and Cochrane CENTRAL databases for studies...
Antiretroviral adherence interventions: Translating research findings to the real world clinic
The success of potent combination antiretroviral therapy (ART) for HIV infection is compromised primarily by failure to maintain optimal levels of adherence over the long term. Recent reviews suggest behavioral...
Human immunodeficiency virus and depression in primary care: A clinical review
Background: Human immunodeficiency virus (HIV)-infected individuals are at increased risk of developing depression. Depressive syndromes in these patients pose a challenge both diagnostically and therapeutically. These syndromes reflect both the...
Mental health service delivery in South Africa from 2000 to 2010: One step forward, one step back
Objectives. To identify progress and challenges in mental healthcare in South Africa, as well as future mental health services research priorities. Method. A systematic review of mental health services research....
HIV infection associated post-traumatic stress disorder and post-traumatic growth – A systematic review
The phenomenon of post-traumatic stress has been well documented in the literature as a lasting mental health condition associated with exposure to traumatic life events. The diagnosis and experience of...
Depression and HIV/AIDS treatment nonadherence: A review and meta-analysis
We meta-analyzed the relationship between depression and HIV medication nonadherence to calculate the overall effect size and examine potential moderators. Overall, across 95 independent samples, depression was significantly (P <...
