Category Archives: Neurocognitive disorders
Differential genotypic evolution of HIV-1 quasispecies in cerebrospinal fluid and plasma: A systematic review
HIV-1 enters the central nervous system by passing the blood-brain barrier during primary infection. Despite the introduction of combination antiretroviral therapy, the prevalence of HIV-associated neurocognitive disorders remains high and...
The relationship between HIV and prevalence of disabilities in sub-Saharan Africa: Systematic review
OBJECTIVE: To systematically review evidence on the prevalence and risk of disabilities among children and adults living with HIV in sub-Saharan Africa. METHODS: Articles were identified from 1980 to June...
Psychological interventions for common mental disorders for people living with HIV in low- and middle-income countries: Systematic review
OBJECTIVE: To assess the effectiveness of structured psychological interventions against common mental disorders (CMD) in people living with HIV infection (PLWH), in low- and middle-income countries (LMIC). METHODS: Systematic review...
Gene expression in HIV-associated neurocognitive disorders: A meta-analysis
OBJECTIVES: To identify differentially expressed (DE) genes in HIV-associated neurocognitive disorders (HAND) patients in comparison with HIV-infected patients without HAND and controls. DESIGN: A meta-analysis of publicly available gene expression...
Validity of cognitive screens for HIV-associated neurocognitive disorder: A systematic review and an informed screen selection guide.
Various screening tools have been proposed to identify HIV-Associated Neurocognitive Disorder (HAND). However, there has been no systematic review of their strengths and weaknesses in detecting HAND when compared to...
Diagnostic accuracy of the International HIV Dementia Scale and HIV Dementia Scale: A meta-analysis.
This aim of this study was to assess the diagnostic accuracy of the International HIV Dementia Scale (IHDS) or HIV Dementia Scale (HDS) for the diagnosis of HIV-associated neurocognitive disorders...