Category Archives: Neurocognitive disorders

The electrophysiology of neuroHIV: A systematic review of EEG and MEG studies in people with HIV infection since the advent of highly-active antiretroviral therapy

2017

OBJECTIVE: The Human Immunodeficiency Virus (HIV) has an impact on the brain, even when the infection is well-controlled with modern highly-active antiretroviral therapy (HAART). While dementia is rare in those...

PET brain imaging in HIV-associated neurocognitive disorders (HAND) in the era of combination antiretroviral therapy

2017

Effective combination antiretroviral therapy (cART) has lead to a significant reduction in the prevalence and incidence of central nervous system (CNS) HIV-associated brain disease, particularly CNS opportunistic infections and HIV...

HIV-associated cognitive impairment in perinatally infected children: A meta-analysis

2016

CONTEXT: Research shows, conclusively, that perinatal HIV infection has negative effects on cognitive functioning of children and adolescents. However, the extent of these cognitive impairments is unknown. Current literature does...

A review of trials investigating efavirenz-induced neuropsychiatric side effects and the implications

2016

Efavirenz is part of the first-line treatment for HIV patients including those in South Africa with approximately 50% experiencing neuropsychiatric side effects. A systematic review of papers reporting neuropsychiatric side...

Cognitive impairment in HIV and HCV co-infected patients: A systematic review and meta-analysis

2016

Cognitive impairment has been well documented in human immunodeficiency virus (HIV) and hepatitis C virus (HCV) mono-infections. However, in the context of HIV/HCV co-infection the research is more limited. The...

Review of functional MRI in HIV: Effects of aging and medication

2016

HIV-associated neurocognitive disorder (HAND) is a frequently occurring comorbidity of HIV infection. Evidence suggests this condition starts subclinical before a progression to a symptomatic stage. Blood oxygenated level dependent (BOLD)...

The mental health of people living with HIV in China, 1998-2014: A systematic review

2016

BACKGROUND: Understanding the mental health burdens faced by people living with HIV in China is instrumental in the development of successful targeted programs for psychological support and care. METHODS: Using...

The influence of neurocognitive impairment on HIV risk behaviors and intervention outcomes among high-risk substance users: A systematic review

2016

Neurocognitive impairment (NCI) among high-risk substance users poses a substantial barrier to reducing risk behaviors in this population. Previous work suggests that NCI is intertwined in a close, reciprocal relationship...

Psychological interventions for common mental disorders for people living with HIV in low- and middle-income countries: Systematic review

2015

OBJECTIVE: To assess the effectiveness of structured psychological interventions against common mental disorders (CMD) in people living with HIV infection (PLWH), in low- and middle-income countries (LMIC). METHODS: Systematic review...

Gene expression in HIV-associated neurocognitive disorders: A meta-analysis

2015

OBJECTIVES: To identify differentially expressed (DE) genes in HIV-associated neurocognitive disorders (HAND) patients in comparison with HIV-infected patients without HAND and controls. DESIGN: A meta-analysis of publicly available gene expression...

Evidence informing the intersection of HIV, aging and health: A scoping review

2014

The growing number of people over age 50 with HIV requires research, policy, and practice to develop a more comprehensive understanding of the health consequences of HIV in older individuals....

Validity of cognitive screens for HIV-associated neurocognitive disorder: A systematic review and an informed screen selection guide.

2013

Various screening tools have been proposed to identify HIV-Associated Neurocognitive Disorder (HAND). However, there has been no systematic review of their strengths and weaknesses in detecting HAND when compared to...

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