Category Archives: Neurocognitive disorders

Evidence informing the intersection of HIV, aging and health: A scoping review

2014

The growing number of people over age 50 with HIV requires research, policy, and practice to develop a more comprehensive understanding of the health consequences of HIV in older individuals....

Validity of cognitive screens for HIV-associated neurocognitive disorder: A systematic review and an informed screen selection guide.

2013

Various screening tools have been proposed to identify HIV-Associated Neurocognitive Disorder (HAND). However, there has been no systematic review of their strengths and weaknesses in detecting HAND when compared to...

Differential genotypic evolution of HIV-1 quasispecies in cerebrospinal fluid and plasma: A systematic review

2013

HIV-1 enters the central nervous system by passing the blood-brain barrier during primary infection. Despite the introduction of combination antiretroviral therapy, the prevalence of HIV-associated neurocognitive disorders remains high and...

The relationship between HIV and prevalence of disabilities in sub-Saharan Africa: Systematic review

2015

OBJECTIVE: To systematically review evidence on the prevalence and risk of disabilities among children and adults living with HIV in sub-Saharan Africa. METHODS: Articles were identified from 1980 to June...

Reaction time slowing in adults with HIV: Results of a meta-analysis using brinley plots

2002

A meta-analysis in the form of Brinley plots was conducted on the mean reaction times of HIV+ and HIV- groups. HIV+ reaction times were regressed on HIV- reaction times across...

What do we know about older adults and HIV? A review of social and behavioral literature

2011

The fastest growing segment of the United States HIV population is people aged 50 and older. This heterogeneous group includes people with diverse pathways into HIV positive status in later...

Evaluation of brief screening tools for neurocognitive impairment in HIV/AIDS: A systematic review of the literature

2013

OBJECTIVE(S): To systematically review literature on brief screening tools used to detect and differentiate between normal cognition and neurocognitive impairment and HIV-associated neurocognitive disorders (HANDs) in adult populations of persons...

A systematic review examining whether interventions are effective in reducing cognitive delay in children infected and affected with HIV

2014

Cognitive delay has been recorded in children infected and affected by HIV. This finding is well established, yet few countries report provision of special educational interventions for this group of...

HIV infection and the fronto-striatal system: A systematic review and meta-analysis of fMRI studies

2014

Functional MRI studies investigating the impact HIV on the brain have implicated the involvement of fronto-striatal circuitry. However, to date there is no review and meta-analysis of this work. We...

Does antiretroviral therapy improve HIV-associated cognitive impairment? A quantitative review of the literature

2011

The development of antiretroviral therapy (ART) has dramatically improved survival for those living with human immunodeficiency virus (HIV), but whether ART improves cognitive functioning remains unclear. The aim of the...

The Impact of DSM-IV Mental Disorders on Adherence to Combination Antiretroviral Therapy Among Adult Persons Living with HIV/AIDS: A Systematic Review

2012

This is a systematic review of eighty-two published studies investigating the impact of DSM-IV mental disorders on combination antiretroviral therapy (cART) adherence and persistence among persons living with HIV/AIDS (PLWHA)....

What is the relevance of mental health to HIV/AIDS care and treatment programs in developing countries? A systematic review

2006

The expansion of AIDS treatment initiatives in resource-poor settings provides an opportunity for integrating mental health care into these programs. This systematic review of the literature on HIV and mental...

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