Category Archives: Neurocognitive disorders

Systematic review of neuroimaging studies in vertically transmitted HIV positive children and adolescents

2014

One of the most serious consequences of vertical HIV-infection is its impact on the central nervous system (CNS). Although much work has been done to elucidate the complex mechanism of...

Psychological interventions for common mental disorders for people living with HIV in low- and middle-income countries: Systematic review

2015

OBJECTIVE: To assess the effectiveness of structured psychological interventions against common mental disorders (CMD) in people living with HIV infection (PLWH), in low- and middle-income countries (LMIC). METHODS: Systematic review...

Gene expression in HIV-associated neurocognitive disorders: A meta-analysis

2015

OBJECTIVES: To identify differentially expressed (DE) genes in HIV-associated neurocognitive disorders (HAND) patients in comparison with HIV-infected patients without HAND and controls. DESIGN: A meta-analysis of publicly available gene expression...

Evidence informing the intersection of HIV, aging and health: A scoping review

2014

The growing number of people over age 50 with HIV requires research, policy, and practice to develop a more comprehensive understanding of the health consequences of HIV in older individuals....

Validity of cognitive screens for HIV-associated neurocognitive disorder: A systematic review and an informed screen selection guide.

2013

Various screening tools have been proposed to identify HIV-Associated Neurocognitive Disorder (HAND). However, there has been no systematic review of their strengths and weaknesses in detecting HAND when compared to...

A meta-analysis of the neuropsychological sequelae of HIV infection

2002

This meta-analysis summarizes the broad spectrum of neuropsychological research on HIV disease across a sample of 41 primary studies and an aggregate of 8,616 participants for 10 major neuropsychological ability...

Placebo response changes depending on the neuropathic pain syndrome: Results of a systematic review and meta-analysis

2012

Objective. To compare placebo responses in neuropathic pain syndromes. Design. Systematic literature review and meta-analysis. Setting and Patients. Randomized placebo-controlled trials assessing pain intensity or pain relief in any neuropathic...

HIV/AIDS and mental health research in sub-Saharan Africa: A systematic review

2011

The relationship between mental illness and HIV/AIDS is complex and bidirectional. A significant amount of research has been performed in high-income countries but less is known about HIV and mental...

Reaction time slowing in adults with HIV: Results of a meta-analysis using brinley plots

2002

A meta-analysis in the form of Brinley plots was conducted on the mean reaction times of HIV+ and HIV- groups. HIV+ reaction times were regressed on HIV- reaction times across...

What do we know about older adults and HIV? A review of social and behavioral literature

2011

The fastest growing segment of the United States HIV population is people aged 50 and older. This heterogeneous group includes people with diverse pathways into HIV positive status in later...

Evaluation of brief screening tools for neurocognitive impairment in HIV/AIDS: A systematic review of the literature

2013

OBJECTIVE(S): To systematically review literature on brief screening tools used to detect and differentiate between normal cognition and neurocognitive impairment and HIV-associated neurocognitive disorders (HANDs) in adult populations of persons...

A systematic review examining whether interventions are effective in reducing cognitive delay in children infected and affected with HIV

2014

Cognitive delay has been recorded in children infected and affected by HIV. This finding is well established, yet few countries report provision of special educational interventions for this group of...

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