Category Archives: Neurocognitive disorders

Sex differences in neurocognitive function in adults with HIV: Patterns, predictors, and mechanisms

2019

PURPOSE OF REVIEW: Sex differences in cognitive function are well documented yet few studies had adequate numbers of women and men living with HIV (WLWH; MLWH) to identify sex differences...

Assessment of neurocognitive deficits in people living with HIV in Sub Saharan Africa: A systematic review

2019

Objective: People living with HIV (PLWH) are at risk for HIV-Associated Neurocognitive Disorders (HAND)/Neurocognitive Impairment (NCI). HIV prevalence in Sub-Saharan Africa (SSA) is high, but neuropsychological screening and testing for...

Optimal treatment of HIV-associated neurocognitive disorders: myths and reality. A critical review

2019

Background: The aim of this study was to review the clinical data on the effectiveness of the pharmacotherapy of HIV-associated neurocognitive disorders (HANDs). Methods: A literature search of PubMed was...

In utero exposure to HIV and/or antiretroviral therapy: A systematic review of preclinical and clinical evidence of cognitive outcomes

2019

INTRODUCION: With the increasing number of children exposed to HIV or antiretroviral therapy in utero, there are concerns that this population may have worse neurodevelopmental outcomes compared to those who...

Different roles of frontal versus striatal atrophy in HIV-associated neurocognitive disorders

2019

Gray matter (GM) atrophy is frequently detected in persons living with HIV, even in the era of combination antiretroviral therapy (cART), but the specificity of regions affected remains elusive. For...

HIV, depression, and cognitive impairment in the era of effective antiretroviral therapy

2019

PURPOSE OF REVIEW: Mental health disorders, especially depression, are prevalent among people living with HIV (PLWH) and are associated with cognitive impairment (CI) among HIV-uninfected (HIV-) individuals. We conducted a...

Psychosocial issues for older adults living with HIV/AIDS

2011

Key take-home messages Older adults may be at greater risk of HIV-related neurocognitive dysfunction and several stressors are associated with aging with HIV, including ageism, HIV-related stigma, declines in social...

Common conditions and diseases in HIV-positive men who have sex with men

2014

Key take-home messages HIV-positive men who have sex with men who experience many physical health conditions at significantly higher rates than their peers who are HIV-negative and the general population,...

Transitioning from adolescent to adult care in HIV

2015

Key take-home messages A range of social, psychological, economic, structural and cultural factors affect adolescents’ ability to transition from pediatric HIV care to adult care. Compared to HIV-negative adolescents, adolescents...

Predictors of human immunodeficiency virus (HIV) infection in primary care among adults living in developed countries: A systematic review

2018

BACKGROUND: Early diagnosis of human immunodeficiency virus (HIV) is important because antiretroviral therapies are more effective if infected individuals are diagnosed early. Diagnosis of HIV relies on laboratory testing and...

A review of long-term toxicity of antiretroviral treatment regimens and implications for an aging population

2018

Human immunodeficiency virus (HIV) is a chronic infectious disease currently requiring lifelong antiretroviral therapy (ART). People living with HIV (PLWH) face an increased risk of comorbidities associated with aging, chronic...

Exercise and cognitive function in people living with HIV: A scoping review

2018

BACKGROUND: Since the advent of antiretrovirals, people with HIV are living longer and have improved quality of life. However, 30-60% of these individuals experience cognitive impairment. Fortunately, physical activity has...

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