Category Archives: Mental Health
The benefits of psychosocial interventions for mental health in people living with HIV: A systematic review and meta-analysis
In this systematic review and meta-analysis we investigated the effectiveness of different psychosocial treatments for people living with HIV (PLWH) and mental health problems. Additionally, characteristics that may influence the...
Anxiety symptoms and disorders among adults living with HIV and AIDS: A critical review and integrative synthesis of the empirical literature
There are over 35 million people worldwide infected with the Human Immunodeficiency Virus (HIV) and its progression to Acquired Immunodeficiency Syndrome (AIDS; WHO, 2014). With the advent of combined antiretroviral...
A review of trials investigating efavirenz-induced neuropsychiatric side effects and the implications
Efavirenz is part of the first-line treatment for HIV patients including those in South Africa with approximately 50% experiencing neuropsychiatric side effects. A systematic review of papers reporting neuropsychiatric side...
PET brain imaging in HIV-associated neurocognitive disorders (HAND) in the era of combination antiretroviral therapy
Effective combination antiretroviral therapy (cART) has lead to a significant reduction in the prevalence and incidence of central nervous system (CNS) HIV-associated brain disease, particularly CNS opportunistic infections and HIV...
HIV-associated cognitive impairment in perinatally infected children: A meta-analysis
CONTEXT: Research shows, conclusively, that perinatal HIV infection has negative effects on cognitive functioning of children and adolescents. However, the extent of these cognitive impairments is unknown. Current literature does...
The relationship between self-blame for the onset of a chronic physical health condition and emotional distress: A systematic literature review
OBJECTIVE: Past literature presents contrasting perspectives regarding the potential influence of self-blame on adjustment to illness. This systematic literature review aimed to summarize findings from all investigations to date that...
Patient-reported barriers to adherence to antiretroviral therapy: A systematic review and meta-analysis
BACKGROUND: Maintaining high levels of adherence to antiretroviral therapy (ART) is a challenge across settings and populations. Understanding the relative importance of different barriers to adherence will help inform the...
Cognitive impairment in HIV and HCV co-infected patients: A systematic review and meta-analysis
Cognitive impairment has been well documented in human immunodeficiency virus (HIV) and hepatitis C virus (HCV) mono-infections. However, in the context of HIV/HCV co-infection the research is more limited. The...
Review of functional MRI in HIV: Effects of aging and medication
HIV-associated neurocognitive disorder (HAND) is a frequently occurring comorbidity of HIV infection. Evidence suggests this condition starts subclinical before a progression to a symptomatic stage. Blood oxygenated level dependent (BOLD)...
Mental disorders in HIV/HCV coinfected patients under antiviral treatment for hepatitis C
This paper aims to review the epidemiology and management of mental disorders in human immunodeficiency virus (HIV)/hepatitis C virus (HCV) coinfected patients, the need for antiviral therapy in this specific...
