Category Archives: Mental Health
Drug-drug interactions with antiviral agents in people who inject drugs (PWID) requiring substitution therapy
OBJECTIVE: To describe potential drug-drug interactions in the area of HIV/hepatitis C virus (HCV) coinfection and injection drug use, including those between antiretrovirals (ARVs), direct-acting antivirals (DAAs), and opioid-agonist therapy,...
Syndemics of psychosocial problems and HIV risk: A systematic review of empirical tests of the disease interaction concept
In the theory of syndemics, diseases co-occur in particular temporal or geographical contexts due to harmful social conditions (disease concentration) and interact at the level of populations and individuals, with...
Differential genotypic evolution of HIV-1 quasispecies in cerebrospinal fluid and plasma: A systematic review
HIV-1 enters the central nervous system by passing the blood-brain barrier during primary infection. Despite the introduction of combination antiretroviral therapy, the prevalence of HIV-associated neurocognitive disorders remains high and...
Psychological interventions for common mental disorders for people living with HIV in low- and middle-income countries: Systematic review
OBJECTIVE: To assess the effectiveness of structured psychological interventions against common mental disorders (CMD) in people living with HIV infection (PLWH), in low- and middle-income countries (LMIC). METHODS: Systematic review...
The relationship between HIV and prevalence of disabilities in sub-Saharan Africa: Systematic review
OBJECTIVE: To systematically review evidence on the prevalence and risk of disabilities among children and adults living with HIV in sub-Saharan Africa. METHODS: Articles were identified from 1980 to June...
Perinatal depression in HIV-infected African women: A systematic review
OBJECTIVE: To systematically review the literature on prevalence and incidence of perinatal depression in human immunodeficiency virus (HIV)-infected African women. DATA SOURCES: We searched 17 databases, including PubMed, PsycINFO, Cochrane,...
Experience of persistent psychological symptoms and perceived stigma among people with HIV on antiretroviral therapy (ART): A systematic review
BACKGROUND: Advances in HIV care have resulted in increasing numbers of HIV patients receiving antiretroviral therapy and achieving viral control. This has led to a focus on the biomedical aspects...
Gene expression in HIV-associated neurocognitive disorders: A meta-analysis
OBJECTIVES: To identify differentially expressed (DE) genes in HIV-associated neurocognitive disorders (HAND) patients in comparison with HIV-infected patients without HAND and controls. DESIGN: A meta-analysis of publicly available gene expression...
Improving mental health among people living with HIV: A review of intervention trials in low- and middle-income countries
People living with HIV (PLWH) experience greater psychological distress than the general population. Evidence from high-incomes countries suggests that psychological interventions for PLWH can improve mental health symptoms, quality of...
The syndemic illness of HIV and trauma: Implications for a trauma-informed model of care
BACKGROUND: People living with HIV infection are disproportionately burdened by trauma and the resultant negative health consequences, making the combination of HIV infection and trauma a syndemic illness. Despite the...
