Category Archives: Mental Health
Gene expression in HIV-associated neurocognitive disorders: A meta-analysis
OBJECTIVES: To identify differentially expressed (DE) genes in HIV-associated neurocognitive disorders (HAND) patients in comparison with HIV-infected patients without HAND and controls. DESIGN: A meta-analysis of publicly available gene expression...
Syndemics of psychosocial problems and HIV risk: A systematic review of empirical tests of the disease interaction concept
In the theory of syndemics, diseases co-occur in particular temporal or geographical contexts due to harmful social conditions (disease concentration) and interact at the level of populations and individuals, with...
The syndemic illness of HIV and trauma: Implications for a trauma-informed model of care
BACKGROUND: People living with HIV infection are disproportionately burdened by trauma and the resultant negative health consequences, making the combination of HIV infection and trauma a syndemic illness. Despite the...
Psychological interventions for common mental disorders for people living with HIV in low- and middle-income countries: Systematic review
OBJECTIVE: To assess the effectiveness of structured psychological interventions against common mental disorders (CMD) in people living with HIV infection (PLWH), in low- and middle-income countries (LMIC). METHODS: Systematic review...
Substance abuse treatment in persons with HIV/AIDS: Challenges in managing triple diagnosis
Clinical management of HIV must account for the “triple diagnosis” of HIV, psychiatric diagnosis, and substance use disorders and requires integrated treatment services that focus beyond just mitigation of substance...
Cognitive-behavioural interventions for mood and anxiety disorders in HIV: A systematic review
BACKGROUND: Mood and anxiety disorders are highly prevalent and comorbid with HIV/AIDS. However, there is a paucity of research on the effectiveness of cognitive-behavioural interventions (CBI) for common mental disorders...
Effectiveness of aerobic exercise in adults living with HIV/AIDS: Systematic review
PURPOSE: The objective of this systematic review was to examine the effectiveness and safety of aerobic exercise interventions on immunological/virological, cardiopulmonary, and psychological outcomes in adults living with HIV/AIDS. METHODS:...
Cognitive-behavioural therapy for depression in people with a somatic disease: Meta-analysis of randomised controlled trials
BACKGROUND: Meta-analyses on psychological treatment for depression in individuals with a somatic disease are limited to specific underlying somatic diseases, thereby neglecting the generalisability of the interventions. AIMS: To examine...
Does antiretroviral therapy improve HIV-associated cognitive impairment? A quantitative review of the literature
The development of antiretroviral therapy (ART) has dramatically improved survival for those living with human immunodeficiency virus (HIV), but whether ART improves cognitive functioning remains unclear. The aim of the...
A systematic review of the screening accuracy of the HIV Dementia Scale and International HIV Dementia Scale
BACKGROUND: The HIV Dementia Scale (HDS) and International HIV Dementia Scale (IHDS) are brief tools that have been developed to screen for and aid diagnosis of HIV-associated dementia (HAD). They...
