Category Archives: Mental Health
Depression and adherence to antiretroviral therapy in low-, middle- and high-income countries: A systematic review and meta-analysis
We investigated the associations between depressive symptoms and adherence to antiretroviral therapy (ART) among people living with HIV (PLHIV). We searched the PubMed, EMBASE and Cochrane CENTRAL databases for studies...
Targeting the SAVA (Substance Abuse, Violence, and AIDS) syndemic among women and girls: A global review of epidemiology and integrated interventions
OBJECTIVES: Multiple pathways link gender-based violence (GBV) to HIV and other sexually transmitted infections among women and girls who use or inject drugs. The aim of this article is to...
Efavirenz-based regimens in antiretroviral-naive HIV-infected patients: A systematic review and meta-analysis of randomized controlled trials
Efavirenz, a non-nucleoside reverse-transcriptase inhibitor (NNRTI) is one of the most commonly prescribed antiretroviral drugs. The present article provides a systematic overview and meta-analysis of clinical trials comparing efavirenz and...
Comparative safety and neuropsychiatric adverse events associated with efavirenz use in first-line antiretroviral therapy: A systematic review and meta-analysis of randomized trials
INTRODUCTION: Efavirenz (EFV) is widely used for the treatment of antiretroviral-naive HIV-positive individuals, but there are concerns about the risk of adverse neuropsychiatric events. We systematically reviewed the safety of...
Meta-analysis of the relationship between HIV infection and risk for depressive disorders
Objective: Each of 10 published studies investigating the relationship between HIV infection and risk for depressive disorders concluded that HIV-positive individuais are at no greater risk for depression than comparable...
What is the evidence for effectiveness of interventions to enhance coping among people living with HIV disease? A systematic review
As new treatments enhance mortality, and infection rates continue to grow in many communities, the concept of “living well” with human immunodeficiency virus (HIV) infection is essential. The concept of...
Understanding HIV-related posttraumatic stress disorder in South Africa: A review and conceptual framework
A number of epidemiological studies have attempted to measure the prevalence of HIV-related posttraumatic stress disorder (PTSD) in sub-Saharan Africa. A systematic review of the literature identified eight relevant studies...
Cancer and the ‘other’ noncommunicable chronic diseases in older people living with HIV/AIDS in resource-limited settings: A challenge to success
Objective: There is considerable research around the morbidity and mortality related to noncommunicable diseases (NCDs), particularly cardiovascular disease and diabetes, among people living with HIV/AIDS (PLWHA) in resource-richer settings. Less...
A role for depression in sexual risk reduction for women? A meta-analysis of HIV prevention trials with depression outcomes
Rates of HIV/AIDS and depression in women are significant public health concerns. The current meta-analysis tested the hypothesis that depression levels moderate change in sexual risk behavior in women participating...
Promoting HIV and sexual safety behaviour in people with severe mental illness: A systematic review of behavioural interventions
People diagnosed with severe mental illness (SMI) are at greater risk of HIV than the general population. However, little attention has been given to how best to reduce sexual risk...
HIV infection associated post-traumatic stress disorder and post-traumatic growth – A systematic review
The phenomenon of post-traumatic stress has been well documented in the literature as a lasting mental health condition associated with exposure to traumatic life events. The diagnosis and experience of...
