Category Archives: Population(s)
Choosing between dual and three-drug antiretroviral therapy in aging and comorbid people with HIV: A narrative review
The widespread use of combination antiretroviral therapy has transformed HIV infection into a chronic condition, with life expectancy of people with HIV (PWH) approaching that of the general population when...
Dysregulated metabolism in people living with HIV in the modern ART-era: A systematic review of targeted metabolomics studies
HIV remains a significant public health issue, with 1.3 million new infections and 630,000 deaths annually, and 40.8 million people living with HIV (PLHIV) globally in 2024. Although antiretroviral therapy...
Maternal-to-child-transmission of human immunodeficiency virus in maternal preterm premature rupture of the membranes: A systematic review
Aim: Preterm premature rupture of membranes (PPROM) in the context of maternal human immunodeficiency virus (HIV) infection poses a significant clinical dilemma, as clinicians must balance the risks of prematurity with...
Barriers and facilitators to oral HIV pre-exposure prophylaxis use in Australia: A scoping review comparing findings to Canada, New Zealand, and the United Kingdom
Oral HIV pre-exposure prophylaxis (PrEP) is highly effective, yet various barriers limit its potential as a HIV prevention strategy. This scoping review aimed to identify and quantify determinants of oral...
Perinatal outcomes associated with antiretroviral therapy for pregnant women living with HIV: An umbrella review
Background: The World Health Organization recommends antiretroviral therapy (ART) for pregnant women living with HIV (WLHIV), the vast majority of whom reside in sub-Saharan Africa. In recent years, many systematic reviews,...
Effectiveness of digital interventions in reducing chemsex-related health risks among mem who have sex with men (MSM): A systematic review
Chemsex among men who have sex with men (MSM) has emerged as a significant public health concern, creating an urgent need for effective harm-reduction strategies. Digital platforms are becoming a...
Implementation of therapeutic adherence in adult patients diagnosed with the human immunodeficiency virus: A systematic review
OBJECTIVES: To systematically map and summarize the available knowledge on interventions that promote medication adherence among adult HIV patients and to describe the current state of the art regarding the...
Indirect treatment comparison of the efficacy of long-acting injectable cabotegravir compared with lenacapavir for HIV pre-exposure prophylaxis
INTRODUCTION: Long-acting injectable cabotegravir (hereafter referred to as cabotegravir) is the first long-acting injectable approved for pre-exposure prophylaxis (PrEP) based on the HPTN 083 and 084 trials. Long-acting injectable lenacapavir...
Interventions to increase adherence to antiretroviral therapy in people living with HIV—what works? A systematic review and meta-analysis
The Perceptions and Practicalities Approach (PaPA) is a recommended framework for designing medication adherence interventions. Little is known about the utility of the PaPA framework in improving antiretroviral therapy (ART)...
Screening for asymptomatic sexually transmitted infections in emergency departments: An integrative review of public health outcomes
OBJECTIVE: To synthesise evidence on opportunistic screening for asymptomatic sexually transmitted infections and bloodborne viruses (STI/BBV) in emergency departments (EDs), focusing on detection, public health outcomes and feasibility. METHODS: An...
Disparities in awareness, willingness and uptake of biomedical HIV prevention among bisexual and gay men: A systematic review and meta-analysis
INTRODUCTION: The field of HIV/STI prevention research has primarily focused on gay men, leaving bisexual men overshadowed in broader discussions on sexual minority men’s health. Although also at increased risk...
Effectiveness of digital health interventions on antiretroviral therapy adherence among people living with HIV in India: A systematic review with an RCT-only meta-analysis
The widespread use of combination antiretroviral therapy has transformed HIV infection into a chronic condition, with life expectancy of people with HIV (PWH) approaching that of the general population when...
