Category Archives: Population(s)

Implementation of therapeutic adherence in adult patients diagnosed with the human immunodeficiency virus: A systematic review

2026

OBJECTIVES: To systematically map and summarize the available knowledge on interventions that promote medication adherence among adult HIV patients and to describe the current state of the art regarding the...

Indirect treatment comparison of the efficacy of long-acting injectable cabotegravir compared with lenacapavir for HIV pre-exposure prophylaxis

2026

INTRODUCTION: Long-acting injectable cabotegravir (hereafter referred to as cabotegravir) is the first long-acting injectable approved for pre-exposure prophylaxis (PrEP) based on the HPTN 083 and 084 trials. Long-acting injectable lenacapavir...

Interventions to increase adherence to antiretroviral therapy in people living with HIV—what works? A systematic review and meta-analysis

2026

The Perceptions and Practicalities Approach (PaPA) is a recommended framework for designing medication adherence interventions. Little is known about the utility of the PaPA framework in improving antiretroviral therapy (ART)...

Screening for asymptomatic sexually transmitted infections in emergency departments: An integrative review of public health outcomes

2026

OBJECTIVE: To synthesise evidence on opportunistic screening for asymptomatic sexually transmitted infections and bloodborne viruses (STI/BBV) in emergency departments (EDs), focusing on detection, public health outcomes and feasibility. METHODS: An...

Disparities in awareness, willingness and uptake of biomedical HIV prevention among bisexual and gay men: A systematic review and meta-analysis

2026

INTRODUCTION: The field of HIV/STI prevention research has primarily focused on gay men, leaving bisexual men overshadowed in broader discussions on sexual minority men’s health. Although also at increased risk...

Effectiveness of digital health interventions on antiretroviral therapy adherence among people living with HIV in India: A systematic review with an RCT-only meta-analysis

2026

The widespread use of combination antiretroviral therapy has transformed HIV infection into a chronic condition, with life expectancy of people with HIV (PWH) approaching that of the general population when...

The global re-emergence of syphilis and antimicrobial resistance among men who have sex with men (MSM), people living with HIV (PLWH), and newborns: A narrative review

2026

Syphilis incidence continues to rise substantially among men who have sex with men (MSM), people living with HIV (PLWH), newborns, and women of reproductive age, despite preventive measures and available...

Prevalence and risk factors for oropharyngeal, esophageal, and oral candidiasis in HIV-positive individuals: A systematic review and meta-analysis

2026

Background: Oral, oropharyngeal, and esophageal candidiasis are common forms of mucosal candidiasis (MC) in people living with human immunodeficiency virus/acquired immunodeficiency syndrome (PLWHA). Despite differences in infection sites, oral, oropharyngeal, and...

The mental health of adults living with HIV in sub-Saharan Africa: Interventions along the HIV care continuum—A systematic review

2026

Although the relationship between HIV and mental health is well-established, limited research has focused on the available interventions for adults living with HIV (ALWH), particularly those in sub-Saharan Africa (SSA)...

Can ChatGPT match physicians in the diagnosis, triage, management and prevention of infectious diseases? A scoping review

2026

INTRODUCTION: The global burden of infectious diseases (ID), combined with a shortage of ID specialists, continues to challenge healthcare systems worldwide. Artificial intelligence (AI), particularly large language models such as...

Effectiveness of HIV status disclosure interventions among children and adolescents in low and middle-income countries: A systematic review

2026

BACKGROUND: Appropriate pediatric HIV status disclosure remains a public health challenge in low- and middle-income countries (LMICs). This review aims to describe the existing pediatric HIV disclosure interventions in LMICs...

Facilitators and barriers to cervical cancer screening among women living with HIV: A systematic review of qualitative studies

2026

BACKGROUND: Evidence suggests that 58% of new cervical cancer cases worldwide occur among women living with HIV. However, compared with HIV-negative women, this population has significantly poorer access to healthcare...

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