Category Archives: Population(s)
Comparative safety of B/F/TAF versus other antiretroviral therapy regimens for treatment-experienced people with HIV-1: A systematic literature review and network meta-analysis
Aim: With modern antiretroviral therapy (ART), HIV-1 has now become a manageable chronic condition. Among treatment-experienced (TE) people with HIV-1 (PWH), ART regimens can influence metabolic and renal outcomes and...
Perinatal HIV in Europe: Clinical advances and psychosocial challenges—A scoping review
Despite significant biomedical advances in the prevention of mother-to-child transmission (MTCT) of HIV, residual transmission and suboptimal maternal outcomes persist across Europe. The challenge is no longer primarily virological but...
Cause of death and risk of death for people living with HIV admitted to hospital: A systematic review and meta-analysis
Introduction Despite increasing access to HIV treatment and care, HIV-associated deaths remain high. We aimed to summarize global and regional trends in risk and causes of death among people living...
Efficacy and safety of doravirine/islatravir for HIV-1: A GRADE-assessed systematic review and meta-analysis of randomized controlled trials
Background: The combination of doravirine and islatravir (DOR/ISL) is a novel two-drug regimen for HIV-1. Early development faced challenges due to dose-dependent immunological signals. We aimed to synthesize the evidence on...
Relationship quality among people living with HIV/AIDS: A systematic review and meta-analysis
Background The aim of this systematic review and meta-analysis was to summarize the existing literature on the factors associated with relationship quality among people living with HIV (PLWH). Method A...
Empowering women living with HIV through partner-based interventions: A scoping review
Spouses and partners play a crucial role in the well-being of women living with HIV (WLWH), especially in family-oriented cultures. This scoping review examined partner-inclusive interventions to strengthen support systems...
Mpox coinfections and clinical manifestation in Africa: A systematic review and meta-analysis
BACKGROUND: Mpox remains a significant public health challenge in Africa, where endemic transmission persists alongside a high burden of other infectious diseases. Although the epidemiology and clinical impact of coinfections...
Prevalence of different genotypes of HIV-1 in injection drug users in China: A systematic review and meta-analysis
Background: Since 1981, an increasing trend in HIV has been observed for transmission via injection drug users (IDUs), sexual transmission and mother-to-child transmission. The IDUs are blamed for early increases...
Psychological distress experiences among patients living with HIV: A qualitative systematic review
BACKGROUND: HIV patients endure psychological distress throughout the phases of diagnosis, treatment, and rehabilitation, which considerably affects their quality of life. A thorough comprehension of patients’ psychological distress experiences is...
Barriers and facilitators of isoniazid preventive therapy implementation among people living with HIV in Nigeria: A scoping review of the literature
BACKGROUND: Implementation of Isoniazid Preventive Therapy (IPT) among People Living with HIV (PLHIV) continues to be a significant challenge, and there is a shortage of effective interventions. This scoping review...
The association between food insecurity and adverse health outcomes in adults: An umbrella review of systematic reviews and meta-analyses
Context An association of food insecurity (FI) with adverse health outcomes (AHOs) has been reported; however, the evidence in this context is still inconclusive. Objective The certainty and validity of...
