Category Archives: Population(s)

Virological failure and adherence to antiretroviral therapy in adolescents and young adults living with human immunodeficiency virus

2023

Objective: HIV (human immunodeficiency virus) infection remains a major public health challenge. Infected young people at any age are less likely to adhere to care in a timely manner and to...

A systematic review and meta-analysis to estimate the time from HIV infection to diagnosis for people with HIV

2022

Timely HIV diagnosis is critical to minimizing transmission events. We sought to estimate the meantime from HIV infection to diagnosis and its temporal trend among people with HIV. Following Preferred...

Prevalence and characteristics of nonalcoholic fatty liver disease and fibrosis in people living with HIV monoinfection: A systematic review and meta-analysis

2023

Background and Aims Liver disease remains a leading cause of morbidity and mortality among people living with HIV (PLWH). Emerging data have shown that PLWH are at high risk for...

Barriers and facilitators to HIV pre-exposure prophylaxis uptake, adherence, and persistence among transgender populations in the United States: A systematic review

2022

HIV pre-exposure prophylaxis (PrEP) is highly effective at preventing HIV; however, PrEP use among transgender individuals remains low. We conducted a systematic review to identify barriers and facilitators to PrEP...

The influence between C-C chemokine receptor 5 (CCR5) genetic polymorphisms and the type-1 human immunodeficiency virus (HIV-1): A 20 years review

2023

Acquired Immune Deficiency Syndrome (AIDS) is an infectious disease caused by the types 1 and 2 Human Immunodeficiency Virus (HIV-1 and HIV-2). Clinical outcomes in patients are highly varied and...

So many harms, so little benefit: A global review of the history and harms of HIV criminalisation

2023

Since the early years of HIV, many jurisdictions have criminalised HIV non-disclosure, potential or perceived exposure, and transmission. Many of these laws and prosecutions are without a scientific basis and...

Factors associated with post-treatment control of viral load in HIV-infected patients: A systematic review and meta-analysis

2023

BACKGROUND: This study aimed to investigate the factors associated with maintenance of viral suppression after antiretroviral therapy (ART) discontinuation. METHODS: Databases were searched for studies published between 1 January, 2011,...

Quantitative methods used to evaluate impact of combination HIV prevention intervention: A methodological systematic review

2023

Combination HIV prevention aims to provide the right mix of biomedical, behavioral and structural interventions, and is considered the best approach to curb the HIV pandemic. The impact evaluation of...

Perinatal outcomes associated with combination antiretroviral therapy compared with monotherapy

2023

Objectives: Increasing numbers of women living with HIV (WLHIV) worldwide receive combination antiretroviral therapy (cART) during pregnancy. We aimed to assess the risk of adverse perinatal outcomes in pregnant WLHIV receiving...

Toxoplasma gondii infection in immunocompromised patients in Iran (2013–2022): A systematic review and meta-analysis

2022

BACKGROUND: Toxoplasma gondii infection (toxoplasmosis) has the potential to cause a serious disease in immunocompromised patients and can be fatal in this population. We conducted a systematic review and meta-analysis...

Cost-effective strategies of testing for HIV and sexually transmitted infections (STIs)

2022

Rates of chlamydia, gonorrhea, and infectious syphilis have risen in Canada from 2015 to 2019. An observed decrease in HIV cases has been detected recently, however a reduction in testing...

Integrating HIV and mental health interventions to address a global syndemic among men who have sex with men

2022

In this Series paper, we review evidence on the co-occurring and synergistic epidemics (syndemic) of HIV and mental health problems worldwide among men who have sex with men (MSM). The...

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