Category Archives: Population(s)
The role of innate immunity in natural elite controllers of HIV-1 infection
The natural process of human immunodeficiency virus type 1(HIV-1) infection is characterized by high viral load, immune cell exhaustion, and immunodeficiency, which eventually leads to the stage of acquired immunodeficiency...
Use of quality-of-life instruments for people living with HIV: A global systematic review and meta-analysis
Introduction: Due to the effectiveness of combined antiretroviral therapy and its growing availability worldwide, most people living with HIV (PLHIV) have a near-normal life expectancy. However, PLHIV continue to face various...
Magnitude and associated factors of urinary tract infections among adults living with HIV in Ethiopia—Systematic review and meta-analysis
BACKGROUND: Urinary tract infection is a major public health problem in developing countries among immunocompromized populations where there are limited health-care services. People living with human immunodeficiency virus (HIV) are...
The impact of genital ulcers on HIV transmission has been underestimated—A critical review
In the early 1990s, several observational studies determined that genital ulcer disease (GUD), in either the index or the exposed person, facilitates HIV transmission. Several meta-analyses have since presented associated...
Impact of antiretroviral therapy on kidney disease in HIV infected individuals—A qualitative systematic review
Kidney disease is the fourth most common cause of non-AIDS-related mortality in people living with HIV. Combination antiretroviral therapy (cART) remains the cornerstone of treatment. However, little is known about...
HIV and STI testing preferences for men who have sex with men in high-income countries: A scoping review
Background: Regular testing for HIV and other sexually transmitted infections (STI) is recommended at least annually for sexually active men who have sex with men (MSM) in most high-income countries....
Effectiveness of interventions for prevention of common infections among opioid users: A systematic review of systematic reviews
BACKGROUND: The North American opioid crisis is marked by high opioid-related mortality and morbidity, including opioid use-associated infections (OUAIs). Users of pharmaceutical and non-pharmaceutical opioids are at an increased risk...
Interventions to improve early retention of patients in antiretroviral therapy programmes in sub-Saharan Africa: A systematic review
BACKGROUND: Several interventions to improve long term retention (12 months and above) on treatment have been rigorously evaluated in Sub-Saharan Africa (SSA). However, research on interventions to improve retention of...
The association between methamphetamine use and number of sexual partners in men who have sex with men: A systematic review and meta-analysis
BACKGROUND: Methamphetamine use in men who have sex with men population is significantly higher than that in the general population. Meth use can cause high-risk sexual behaviors, such as having...
Use of HIV recency assays for HIV incidence estimation and other surveillance use cases: Systematic review
BACKGROUND: HIV assays designed to detect recent infection, also known as “recency assays,” are often used to estimate HIV incidence in a specific country, region, or subpopulation, alone or as...
Men missing from the HIV care continuum in sub-Saharan Africa: A meta-analysis and meta-synthesis
Introduction: Men are missing along the HIV care continuum. However, the estimated proportions of men in sub-Saharan Africa meeting the UNAIDS 95-95-95 goals vary substantially between studies. We sought to estimate...
