Category Archives: Population(s)

Clinical consequences of asymptomatic cytomegalovirus in treated human immunodeficency virus infection

2021

PURPOSE OF REVIEW: Despite antiretroviral therapy (ART)-mediated viral suppression, people with human immunodeficiency virus (HIV) (PWH) have increased morbidity and mortality. Immune activation and inflammation persist on ART and predict...

Frailty: The current challenge for aging people with HIV

2021

PURPOSE OF REVIEW: Older adults account for the majority of people with HIV (PWH) in high-income countries and have increasingly complex clinical profiles related to premature aging. Frailty is an...

Current co-morbidities burden in patients living with HIV in low- and middle-income countries

2021

PURPOSE OF REVIEW: The present review aims to decipher common co-morbidities faced by people living with HIV in low- to middle-income countries, and in particular the sub-Saharan region, which hosts...

Impact of Integrase inhibitors and tenofovir alafenamide on weight gain in people with HIV

2021

PURPOSE OF REVIEW: Obesity is increasing in people with HIV (PWH). This review aims to summarise the recent evidence investigating the associations between the use of integrase inhibitors and tenofovir...

Recent advances in HIV-associated chronic lung disease clinical research

2021

PURPOSE OF REVIEW: To highlight recently published, clinically focused research on chronic lung disease in adult persons with human immunodeficiency virus-1 (HIV) (PWH). RECENT FINDINGS: Chronic lung disease was the...

Recent data on adipose tissue, insulin resistance, diabetes and dyslipidaemia in antiretroviral therapy controlled HIV-infected persons

2021

PURPOSE OF REVIEW: Increased total body fat with truncal redistribution is common in antiretroviral therapy (ART)-controlled persons living with HIV(PLWH), leading to insulin resistance, prediabetes/diabetes and dyslipidaemia. We address these...

A review of the state of the science of HIV and stigma: Context, conceptualization, measurement, interventions, gaps, and future priorities

2021

Stigma is a fundamental cause of health inequities. As such, stigma is a major barrier to HIV prevention, care, and treatment. This review will examine the concept of stigma, explicating...

A review of chronic comorbidities in adults living with HIV: State of the science

2021

People living with HIV are living longer, high-quality lives; however, as they age, this population is at increased risk for developing chronic comorbidities, including cardiovascular disease, certain types of cancer...

The intersection of cognitive ability and HIV: A review of the state of the nursing science

2021

Neurocognitive problems have been endemic to the HIV epidemic since its beginning. Four decades later, these problems persist, but currently, they are attributed to HIV-induced inflammation, the long-term effects of...

Epidemiology estimates of hepatitis D in individuals co-infected with human immunodeficiency virus and hepatitis B virus, 2002–2018: A systematic review and meta-analysis

2021

Hepatitis delta virus (HDV) is an obligate satellite of hepatitis B virus (HBV). HIV/HDV co-infection is associated with a high rate of hepatic decompensation events and death. We aimed to...

Childhood sexual abuse and adult sexual risk behavior: A review and critique

2021

Childhood sexual abuse (CSA) is a global problem with serious repercussions for survivors in various domains of adult interpersonal functioning, including sexual risk behavior. This review aimed to summarize findings...

Comparative efficacy of antifungal agents used in the treatment of oropharyngeal candidiasis among HIV-infected adults: A systematic review and network meta-analysis

2021

The objective of this study was to assess the comparative efficacy and safety of different antifungal agents used for the treatment of oropharyngeal candidiasis (OPC) in adult patients with HIV....

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