Category Archives: Population(s)

Impact of combined antiretroviral therapy on metabolic syndrome components in adult people living with HIV: A literature review

2022

The development of metabolic derangements as a result of HIV treatment has been an important area of research since the introduction of zidovudine in the 1980’s. Antiretroviral therapy has intensely...

A systematic review and meta-analysis of the catastrophic costs incurred by tuberculosis patients

2022

One of the strategies of the World Health Organization End Tuberculosis (TB) was to reduce the catastrophic costs incurred by TB-affected families to 0% by 2020.Catastrophic cost is defined by...

Epigenome-wide epidemiologic studies of human immunodeficiency virus infection, treatment, and disease progression

2022

Despite significant advances in the treatment and care of people with HIV (PWH), several challenges remain in our understanding of disease pathogenesis to improve patient care. HIV infection can modify...

HIV-1 genetic diversity a challenge for AIDS vaccine development: A retrospective bibliometric analysis

2022

Background: Despite recent advances in human immunodeficiency virus-1 (HIV-1) prevention, a fast, safe, and effective vaccine will probably be necessary to end the HIV/AIDS pandemic. This study was conducted to evaluate...

Safety of antiretroviral therapy in the treatment of HIV/AIDS in children: Systematic review and meta-analysis

2021

The safety of using different antiretroviral therapies (ART) in pediatric HIV/AIDS patients is not well-established. Therefore, this study aimed to assess the safety of ART in children. A systematic review...

Acceptability of HIV pre-exposure prophylaxis in China: A systematic review and meta-analysis

2022

Using pre-exposure prophylaxis (PrEP) for the prevention of HIV infection is a popular, contemporary research topic. We retrieved PubMed, Web of Science, MEDLINE, Wanfang, CNKI, and Sinomed databases, and related...

How does HIV persist under antiretroviral therapy: A review of the evidence

2021

HIV-1 is a retrovirus capable of establishing viral reservoirs that remain stable for extended periods under suppressive antiretroviral therapy (ART). Immune dysfunction and latency are well known to contribute to...

Cost-effectiveness of HIV retention and re-engagement interventions in high-income countries: A systematic literature review

2022

Engagement in lifelong HIV care is critical for both patient and public health, yet there are limited resources to invest in improving HIV outcomes. We systematically reviewed evidence on the...

Combinatorial strategies for long-term control of HIV infection

2021

AIDS is a disease caused by a chronic infection of HIV. Recently, long-term control of HIV infection has been demonstrated through the bone marrow transplantation of hematopoietic stem cells (HSC),...

Risk of vertical transmission of chronic viral infections after invasive prenatal procedures

2022

OBJECTIVES: Invasive prenatal procedures including amniocentesis, chorionic villus sampling (CVS) can be prenatally indicated for diagnostic purposes. Chronic viral infections with Human Immunodeficiency Virus (HIV), hepatitis C virus (HCV), hepatitis...

Potential immune modulatory effect of vitamin D in HIV infection: A review

2021

Vitamin D is a fat soluble hormone that is majorly involved in the classical function of calcium and phosphorus hemostasis and bone mineralization as well non classical functions of immune...

Bridging the gap between development of point-of-care nucleic acid testing and patient care for sexually transmitted infections

2022

The incidence rates of sexually transmitted infections (STIs), including the four major curable STIs – chlamydia, gonorrhea, trichomoniasis and, syphilis – continue to increase globally, causing medical cost burden and...

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