Category Archives: Population(s)

Prevalence and risk factors for HIV infection in truck drivers: A systematic review of global evidence

2023

Transporting and driving long distances might be associated with an increased risk of contracting HIV in truck drivers, which is recognized as a link to network transmission of HIV among...

Machine learning for personalized risk assessment of HIV, syphilis, gonorrhoea and chlamydia: A systematic review and meta-analysis

2025

Background Machine learning (ML) shows promise for sexually transmitted infection (STI) risk prediction, but systematic evidence of its effectiveness remains fragmented. Methods We systematically searched six electronic databases, three preprint...

HIV-1 drug resistance in children and implications for pediatric treatment strategies: A systematic review and meta-analysis

2025

Introduction Failure in the prevention of mother-to-child HIV transmission (PMTCT) and pediatric treatment challenges led to pretreatment drug resistance (PDR) and acquired drug resistance (ADR) in children with HIV (CWHIV)....

Meta-analysis of TB & HIV co-infection mortality rate in sub-Saharan African children, youth, and adolescents

2025

Background Despite the effectiveness of antiretroviral treatment (ART) in reducing morbidity and mortality, children and adolescents with co-infections face an elevated risk of death due to their young age and...

The diagnostic significance of the C-reactive protein (CRP) in HIV/TB coinfection: A systematic review and meta-analysis

2025

Background Drug-resistant Mycobacterium tuberculosis strains have challenged efforts to combat tuberculosis (TB), a major global killer. C-reactive protein (CRP) shows promise as a biomarker for TB screening, particularly in HIV-positive...

HIV, hepatitis, and syphilis self-testing among adolescents and young adults: A systematic review and meta-analysis

2025

Background: Adolescents and young adults (AYA) make up a significant share of the world’s burden of HIV and other sexually transmitted infections (STI). Self-testing can increase testing coverage and strengthen the...

Evolving patterns of macrolide and fluoroquinolone resistance in Mycoplasma genitalium: An updated systematic review and meta-analysis

2025

Background: Over the past 5 years, since publication of the initial review, studies have provided additional data on macrolide and fluoroquinolone resistance in Mycoplasma genitalium, including data from regions previously lacking...

Undetectable = Untransmittable: A cross-population systematic review and meta-analysis on awareness and acceptance

2025

The Undetectable = Untransmittable (U=U) message is a cornerstone of HIV-related public health communication, yet global levels of awareness and acceptance remain unclear across key populations. This study aimed to...

Manifestation and markings of HIV stigma in Indonesia: A scoping review

2025

Stigma related to HIV hinders access to healthcare services and worsens the quality of life for people living with HIV (PLHIV). A comprehensive understanding of HIV stigma is crucial for...

Retention in HIV care among Southeast Asian people living with HIV: A systematic review and meta-analysis

2025

Background Despite the effectiveness of antiretroviral therapy (ART) in reducing HIV-related morbidity and mortality, the retention of HIV care remains suboptimal in Southeast Asia. Objective This systematic review and meta-analysis...

A scoping review on HCV screening strategies: Population to screen and the test types

2025

BACKGROUND: Hepatitis C virus (HCV) is a genetically diverse blood-borne pathogen causing liver inflammation and damage. It is one of the global public health problems responsible for claiming thousands of...

Immune responses to vaginal candidiasis in African women: A scoping review of cytokine profiles, T-cell activation, and gene expression

2025

Background Recent immunological studies of vaginal candidiasis in African populations have revealed complex host‒pathogen interactions with implications for therapeutic development and HIV acquisition risk. Objective This scoping review synthesized evidence...

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