Category Archives: Population(s)
Efficacy of long-acting injectable cabotegravir and rilpivirine compared with daily oral antiretroviral therapy in patients with HIV: A systematic review
Long-acting antiretroviral therapy (ART) has emerged as an innovative strategy to address limitations associated with daily oral regimens in people living with human immunodeficiency virus type 1 (HIV-1), including adherence...
A systematic review of models used to estimate undiagnosed HIV prevalence in high-income low-prevalence countries and territories
INTRODUCTION: Estimating undiagnosed HIV prevalence facilitates planning epidemic responses, and monitoring progress towards UNAIDS and national targets. We undertook a systematic review to identify models used to estimate undiagnosed HIV...
Role of pharmacists in HIV prophylaxis: A scoping review of pharmacists’ services, interventions and outcomes
INTRODUCTION: HIV remains a major global public health challenge, with nearly 1.3 million new HIV acquisitions annually. Despite the effectiveness of pre-exposure (PrEP) and post-exposure prophylaxis (PEP), barriers to access,...
Vulnerability and non-adherence to treatment in cisgender women living with HIV/AIDS: A scoping review (2000–2024)
Background Cisgender women are disproportionately affected by HIV/AIDS due to structural gender inequalities and intersecting social determinants, which generate vulnerability contexts that act as barriers to treatment adherence. Methods A...
Knowledge of reproductive-age women about mother-to-child transmission of HIV and associated factors: A systematic review and meta-analysis
INTRODUCTION: Despite significant efforts to manage and prevent HIV, knowledge gaps persist regarding mother-to-child transmission of HIV among women of reproductive age. Previous studies, limited in scope and producing inconsistent...
Virologic suppression among HIV-positive pregnant and lactating women receiving antiretroviral therapy in Africa: A systematic review and meta-analysis
Background The elimination of mother-to-child transmission of human immunodeficiency virus (HIV) is a key global public health priority. In Africa, virologic failure among people living with HIV continues to pose a...
HIV in Iraq: Key populations, sociodemographics, transmission modes, present realities, and urgent next steps: A systematic review
Background and Purpose While empirical studies in Iraq have examined sociodemographic characteristics and modes of human immunodeficiency virus (HIV) transmission, including but not limited to those involving key populations, there...
Effect of BMI on mortality in patients with tuberculosis and HIV coinfection in Asia and Africa: Systematic review and meta-analysis
Background Tuberculosis (TB) continues to pose a major global health threat, particularly in low- and middle-income countries. An estimated 10.8 million people developed TB in 2023, corresponding to 134 cases...
Peer network approaches for improving HIV testing, prevention and care utilisation among men in sub-Saharan Africa: A scoping review
INTRODUCTION: Limited male engagement in HIV prevention and care is a global challenge more pronounced in sub-Saharan Africa (SSA) contributing to ongoing transmission. However, peer network interventions show promise in...
The risk of infection-related malignancies and tumor mutational burden in immunocompromised hosts: A systematic review and meta-analysis
Background Immunocompromised individuals exhibit an increased risk of malignancies attributable to impaired immune surveillance and increased susceptibility to oncogenic infections, resulting in distinct responses to immunotherapy. The intricacies of infection-related...
Risk factors and mortality rates for children co-infected with HIV and TB in Ethiopia: A systematic review and meta-analysis
This systematic review and meta-analysis aimed to identify risk factors and mortality rates in HIV and TB co-infected children in Ethiopia. An electronic literature search was conducted using multiple databases,...
Barriers and facilitators to the diagnosis of HIV and other STIs in primary care within publicly funded healthcare systems: A systematic review of qualitative studies
BACKGROUND: Human immunodeficiency virus (HIV) and other sexually transmitted infections (STI) are a major public health concern. Primary care (PC) is the ideal setting for their diagnosis. Designing effective strategies...
