Category Archives: Population(s)

Complex solutions for a complex problem: A meta-analysis of the efficacy of multiple-behavior interventions on change in outcomes related to HIV

2021

OBJECTIVE: The purpose of this meta-analysis was to examine the success of multiple-behavior interventions and to identify whether the efficacy of such programs depends on the number of recommendations prescribed...

Bioactive compounds as potential agents for sexually transmitted diseases management: A review to explore molecular mechanisms of action

2021

Sexually transmitted diseases (STDs) are produced by pathogens like bacteria, fungi, parasites, and viruses, and may generate severe health problems such as cancer, ulcers, and even problems in the newborn....

Effectiveness of eHealth interventions for HIV prevention and management in sub-Saharan Africa: Systematic review and meta-analyses

2021

HIV is still the leading cause of death in Sub-Saharan Africa (SSA), despite medical advances. eHealth interventions are effective for HIV prevention and management, but it is unclear whether this...

HIV treatment with the two-drug regimen dolutegravir plus lamivudine in real-world clinical practice: A systematic literature review

2021

The two-drug regimen dolutegravir plus lamivudine demonstrated durable efficacy for up to 3 years in phase III studies and a high barrier to resistance in treatment-naive and virologically suppressed people...

Diagnostic value of interferon-I3 release assay in HIV-infected individuals complicated with active tuberculosis: A systematic review and meta-analysis

2021

OBJECTIVE: Although the interferon-I3 release assay (IGRA) has become a common diagnostic method for tuberculosis, its value in the diagnosis of tuberculosis in human immunodeficiency virus (HIV) seropositive patients remains...

Sex differences in HIV testing among older adults in sub-Saharan Africa: A systematic review

2021

BACKGROUND: Despite being sexually active and engaging in risky sexual behaviours similar to young adults, older adults (50 years or older) are less likely to receive HIV testing, and disaggregated...

Cognitive differences between men and women with HIV: A systematic review and meta-analysis

2021

Objective: Although many studies report that women with HIV (WWH) are more vulnerable to cognitive impairment than men with HIV (MWH), this trend is not described consistently in the literature. In...

The catastrophic HPV/HIV dual viral oncogenomics in concert with dysregulated alternative splicing in cervical cancer

2021

Cervical cancer is a public health problem and has devastating effects in low-to-middle-income countries (LTMICs) such as the sub-Saharan African (SSA) countries. Infection by the human papillomavirus (HPV) is the...

HIV continuum of care: Expanding scope beyond a cross-sectional view to include time analysis: A systematic review

2021

INTRODUCTION: The continuum of care (CoC) model has been used to describe the main pillars of HIV care. This study aims to systematically review methods and elucidate gaps in the...

Same-day antiretroviral therapy initiation for people living with HIV who have tuberculosis symptoms: A systematic review

2021

Objectives Tuberculosis symptoms are very common among people living with HIV (PLHIV) initiating antiretroviral therapy (ART), are not specific for tuberculosis disease and may result in delayed ART start. The...

Economic and modeling evidence for tuberculosis preventive therapy among people living with HIV: A systematic review and meta-analysis

2021

BACKGROUND: Human immunodeficiency virus (HIV) is the strongest known risk factor for tuberculosis (TB) through its impairment of T-cell immunity. Tuberculosis preventive treatment (TPT) is recommended for people living with...

Tuberculosis preventive therapy for people living with HIV: A systematic review and network meta-analysis

2021

BACKGROUND: Tuberculosis (TB) preventive therapy (TPT) is an essential component of care for people living with HIV (PLHIV). We compared efficacy, safety, completion, and drug-resistant TB risk for currently recommended...

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