Category Archives: Population(s)

The effect of Rosuvastatin on plasma/serum levels of high sensitivity C-reactive protein, interleukin-6 and D-dimer in people living with iuman immunodeficiency virus: A systematic review and meta-analysis

2021

Rosuvastatin therapy might have an effect on the inflammatory and coagulation biomarkers. However, the evidence about the effect of rosuvastatin therapy on the high-sensitivity C-reactive protein (hsCRP), interleukin-6 (IL-6), and...

Health system adaptations and considerations to facilitate optimal oral pre-exposure prophylaxis scale-up in sub-Saharan Africa

2021

Following WHO’s 2015 recommendation, countries in sub-Saharan Africa have progressively scaled up oral pre-exposure prophylaxis (PrEP) as part of combination HIV prevention. PrEP has potential to significantly reduce new HIV...

A systematic review of magnetic resonance imaging studies in perinatally HIV-infected individuals

2021

Over the past few years, neuroimaging studies have been performed in young adults with perinatally acquired HIV (PHIV) to study the impact of HIV infection on the central nervous system...

The clinical outcomes of COVID-19 in HIV-positive patients: A systematic review of current evidence

2021

INTRODUCTION: Patients with chronic underlying diseases are more susceptible to coronavirus disease 2019 (COVID-19) complications. Recent studies showed people living with HIV (PLWH) are not at greater risk than the...

Neuropsychological effects of direct-acting antiviral treatment for HCV subjects: A systematic review

2021

Direct-acting antivirals (DAAs) have been approved in recent years to treat patients infected by the Hepatitis C virus (HCV). The DAAs treatment is well tolerated and increases sustained virological response...

Global cascade of care for chronic hepatitis C virus infection: A systematic review and meta-analysis

2021

The World Health Organization 2030 targets for hepatitis C virus (HCV) elimination include diagnosing 90% of people with HCV and treating 80% of people diagnosed with HCV. This systematic review...

Cardiovascular risks associated with protease inhibitors for the treatment of HIV

2021

Introduction: Cumulative use of some first-generation protease inhibitors has been associated with higher rates of dyslipidemia and increased risk of cardiovascular disease. The protease inhibitors most commonly in use are...

A systematic review up to 2018 of HIV and associated factors among criminal justice-involved (CJI) Black sexual and gender minority populations in the United States (US)

2021

Black men who have sex with men (BMSM) and Black transgender women (BTW) are impacted by dual epidemics of HIV and incarceration. We advanced understanding of the relationship between criminal...

Association between frailty phenotype, quantification of plasma HIV-1 RNA, CD4 cell count and HAART in HIV-positive subjects: A systematic review and meta-analysis of observational studies

2021

HIV infection causes a constant activation of the immune system and contributes to an enhanced systemic pro-inflammatory cytokine milieu, which has been associated with premature aging and frailty. We performed...

Best practices of using online and geosocial network applications to provide HIV and sexual health information to young newcomer men who have sex with men

2021

There is a high HIV incidence among young gay men and other men who have sex with men in countries such as China in recent years. Evidence shows that HIV...

Laboratory (non-rapid) HIV testing in the emergency department: Methods, outcomes, and effectiveness

2021

There is a large body of evidence examining best practices, outcomes, impact, and other aspects of laboratory (non-rapid) HIV testing in emergency departments (EDs). Many studies have identified missed opportunities...

A review of structural, process, and outcome measures for supervised consumption services

2021

A 2019 systematic review identified several types of outcomes from scientific literature that guide assessment of SCS, including: usage by high-risk individuals, safe injection practice, overdose management, uptake of treatment...

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