Category Archives: Population(s)
Safety, tolerability, and metabolic effects of long-acting cabotegravir and rilpivirine in HIV care: A comprehensive review
The use of long-acting cabotegravir and rilpivirine (LA CAB/RPV) is a novel approach to manage human immunodeficiency virus (HIV). This injectable regimen offers benefits such as an improved quality of...
Barriers and facilitators to engagement with the PrEP care continuum among sexual minority men in China: A systematic review
Sexual minority men (SMM) in China are disproportionately affected by the HIV epidemic, yet utilization of HIV prevention services, such as pre-exposure prophylaxis (PrEP), remains low. This systematic review summarizes...
Exploring the impacts of high-intensity interval training (HIIT) in people living with HIV: A scoping review
People with human immunodeficiency virus (PWH) face increased health risks beyond those directly linked to HIV infection, including reduced cardiorespiratory fitness (CRF), cardiovascular disease, and accelerated aging. Physical exercise, particularly...
Evidence-based interventions targeting mental health problems in adolescents living with HIV: A scoping review
Adolescents living with HIV are at an increased risk of experiencing mental health challenges, impacting their overall well-being and treatment adherence. Evidence-based interventions are crucial to addressing these issues; however,...
Approaches used to monitor the effectiveness of community-led monitoring programmes: A scoping review to inform HIV programmes
INTRODUCTION: Community-led monitoring (CLM) for HIV is a technique implemented by local community-led organizations and groups that systematically gather data about HIV services to advocate for improvement. This review was...
Efficacy and safety of echinocandins combined with Trimethoprim-Sulfamethoxazole as first-line treatment for Pneumocystis pneumonia in HIV-infected and non-HIV-infected patients
Introduction Pneumocystis pneumonia (PCP) is a life-threatening infection in both HIV- infected and non-HIV-infected immunocompromised patients. Although Trimethoprim-Sulfamethoxazole (TMP/SMX) combined with echinocandins has been used clinically, whether this combination is...
Strategies for improving linkage to HIV care after hospital discharge among adults living with HIV in low- and middle-income countries: A systematic review
Purpose Despite the availability of antiretroviral therapy (ART), nearly a quarter of people living with HIV (PLHIV) die within six months after hospital discharge due to complications from AIDS-related illnesses....
Mortality and associated factors among children with the double burden of human immunodeficiency virus and tuberculosis in African countries: A systematic review and meta-analysis
Introduction The dual burden of Human Immunodeficiency Virus (HIV) and Tuberculosis (TB) in children is leading to significant mortality. Although primary studies have reported wide ranges of mortality rates among...
Effects of Moringa oleifera supplementation on immune and nutritional biomarkers in adults living with HIV: A systematic review and meta-analysis
BACKGROUND: Moringa oleifera (MO) is widely used as an adjunctive therapy for individuals living with HIV (PLWH) due to its nutritional and immune-modulating properties. OBJECTIVE: To systematically evaluate the effects...
Effectiveness of conditional cash transfers for uptake and retention in HIV prevention of mother-to-child transmission services in low- and middle-income countries: A systematic review and meta-analysis
OBJECTIVE: The objective of this systematic review was to synthesize the best available evidence on the effectiveness of conditional cash transfers for the uptake and retention in prevention of mother-to-child...
Determinants of HIV related mortality in African children on antiretroviral therapy: Clinical and immunological insights from a systematic review and meta-analysis
BACKGROUND: The HIV epidemic in Africa is still a serious public health concern, particularly for children who are more vulnerable to its negative consequences. Various studies carried out in different...
