Category Archives: Population(s)

Adolescents and age of consent to HIV testing: An updated review of national policies in sub-Saharan Africa

2021

Objectives In sub-Saharan Africa (SSA) where HIV burden is highest, access to testing, a key entry point for prevention and treatment, remains low for adolescents (aged 10–19). Access may be hampered...

A systematic review of neighborhood-level influences on HIV vulnerability

2021

A better understanding of the social-structural factors that influence HIV vulnerability is crucial to achieve the goal of ending the HIV epidemic by 2030. Given the role of neighborhoods in...

Association between adherence to antiretroviral therapy and place of residence among adult HIV infected patients in Ethiopia: A systematic review and meta-analysis

2021

BACKGROUND: According to the World Health Organization, optimal adherence to Antiretroviral Therapy (ART) improves quality of life. Patients who use ART have varying characteristics in terms of where they live....

Barriers and facilitators of rendering HIV services by community health workers in sub-Saharan Africa: A meta-synthesis

2021

OBJECTIVES: To synthesise qualitative studies that address the barriers to and facilitators of providing HIV services by community health workers (CHWs) in sub-Saharan Africa (SSA). DESIGN: This meta-synthesis was guided...

Magnetic resonance imaging as a biomarker in diabetic and HIV-associated peripheral neuropathy: A systematic review-based narrative

2021

Background: Peripheral neuropathy can be caused by diabetes mellitus and HIV infection, and often leaves patients with treatment-resistant neuropathic pain. To better treat this condition, we need greater understanding of...

Global scoping review of HIV prevention research with transgender people: Transcending from trans-subsumed to trans-centred research

2021

INTRODUCTION: Globally, transgender populations are disproportionally impacted by HIV and effective HIV prevention interventions targeting these populations are critically needed. Such interventions require research focused on the specific needs and...

The role of inflammasome activation in early HIV infection

2021

The inflammasome pathway is an important arm of the innate immune system that provides antiviral immunity against many viruses. The main pathways involved in virus infections include the NLRP3, IFI16,...

HIV-sensitive social protection for vulnerable young women in East and Southern Africa: A systematic review

2021

Introduction: Social protection programmes are considered HIV-sensitive when addressing risk, vulnerability or impact of HIV infection. Socio-economic interventions, like livelihood and employability programmes, address HIV vulnerabilities like poverty and gender inequality....

The prevalence of thrombocytopenia and leucopenia among people living with HIV/AIDS in Ethiopia: A systematic review and meta-analysis

2021

INTRODUCTION: Thrombocytopenia and leucopenia are frequently encountered hematological disorders among people living with HIV/AIDS. This systematic review and meta-analysis were aimed to indicate the national prevalence of thrombocytopenia and leucopenia...

HIV self-testing with digital supports as the new paradigm: A systematic review of global evidence (2010–2021)

2021

BACKGROUND: HIV self-testing (HIVST) is recommended by the WHO as an innovative strategy to reach UNAIDS targets to end HIV by 2030. HIVST with digital supports is defined as the...

The catastrophic HPV/HIV dual viral oncogenomics in concert with dysregulated alternative splicing in cervical cancer

2021

Cervical cancer is a public health problem and has devastating effects in low-to-middle-income countries (LTMICs) such as the sub-Saharan African (SSA) countries. Infection by the human papillomavirus (HPV) is the...

HIV continuum of care: Expanding scope beyond a cross-sectional view to include time analysis: A systematic review

2021

INTRODUCTION: The continuum of care (CoC) model has been used to describe the main pillars of HIV care. This study aims to systematically review methods and elucidate gaps in the...

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