Category Archives: Population(s)
Drug resistance mutations in HIV: New bioinformatics approaches and challenges
Drug resistance mutations appear in HIV under treatment pressure. Resistant variants can be transmitted to treatment-naive individuals, which can lead to rapid virological failure and can limit treatment options. Consequently,...
Roles of virion-incorporated CD162 (PSGL-1), CD43, and CD44 in HIV-1 Infection of T Cells
Nascent HIV-1 particles incorporate the viral envelope glycoprotein and multiple host transmembrane proteins during assembly at the plasma membrane. At least some of these host transmembrane proteins on the surface...
Seroprevalence estimates of latent and acute toxoplasma infections in HIV(+) people-call for action in underprivileged communities
We undertook a comprehensive, systematic review of observational studies to estimate respective seroprevalences of latent and acute Toxoplasma gondii infections in HIV(+) people at the global, regional and country levels;...
HIV-proteins-associated CNS neurotoxicity, their mediators, and alternative treatments
Human immunodeficiency virus (HIV)-infected people’s livelihoods are gradually being prolonged with the use of combined antiretroviral therapy (ART). Conversely, despite viral suppression by ART, the symptoms of HIV-associated neurocognitive disorder...
Environmental pollutants, mucosal barriers, and pathogen susceptibility; the case for aflatoxin B(1) as a risk factor for HIV transmission and pathogenesis
HIV transmission risk is dependent on the infectivity of the HIV+ partner and personal susceptibility risk factors of the HIV- partner. The mucosal barrier, as the internal gatekeeper between environment...
TLR-agonist mediated enhancement of antibody-dependent effector functions as strategy for an HIV-1 cure
BACKGROUND: The current treatment for HIV-1 is based on blocking various stages in the viral replication cycle using combination antiretroviral therapy (ART). Even though ART effectively controls the infection, it...
Clinical progression of COVID-19 coinfection in people living with the human immunodeficiency virus: Scoping review
OBJECTIVES: to map the production of scientific knowledge on the clinical progression of COVID-19 coinfection in people living with the human immunodeficiency virus (HIV). METHODS: scoping review, with search strategies...
Post-immigration factors affecting retention in HIV care and viral suppression in Latin American and Caribbean immigrant populations in the United States: A systematic review
Objectives: To reduce disparities in HIV care outcomes among Latin American and Caribbean (LAC) immigrants living with HIV in the U.S., it is necessary to identify factors influencing HIV care in...
Non-vertical exposures to HIV, HBV and HCV infection in children and adolescents-risk of infection, standards of care and postexposure prophylaxis
INTRODUCTION: in the review, we aimed to present current knowledge about the risk of infection, standards of care, and postexposure prophylaxis (PEP) in pediatric patients after non-vertical exposures to HIV,...
Incentive-based human immunodeficiency virus Screening in low and middle income countries: A systematic review
BACKGROUND: The majority of new HIV infections that occur worldwide are in sub-Saharan Africa. While recent gains have been made in many low and middle income countries (LMIC), substantial disparities...
