Category Archives: Population(s)

HSV-2 as a biomarker of HIV epidemic potential in female sex workers: Meta-analysis, global epidemiology and implications

2020

This study investigated herpes simplex virus type 2 (HSV-2) seroprevalence utility as a predictor of HIV epidemic potential among female sex workers (FSWs) globally. We updated and analyzed a systematically-assembled...

Psychiatric disorders in adolescents living with HIV and association with antiretroviral therapy adherence in sub-Saharan Africa: A systematic review and meta-analysis

2020

In sub-Saharan Africa (SSA), a systematic approach to exploring the prevalence of psychiatric disorders (PDs) and adherence to antiretroviral treatment (ART) in adolescents living with HIV (ALWHIV) is lacking. This...

HIV, vascular risk factors, and cognition in the combination antiretroviral therapy era: A systematic review and meta-analysis

2020

OBJECTIVES: Mounting evidence indicates that vascular risk factors (VRFs) are elevated in HIV and play a significant role in the development and persistence of HIV-associated neurocognitive disorder. Given the increased...

Estimates of the global burden of cervical cancer associated with HIV

2021

Background: HIV enhances human papillomavirus (HPV)-induced carcinogenesis. However, the contribution of HIV to cervical cancer burden at a population level has not been quantified. We aimed to investigate cervical cancer...

Sexual behaviour change following HIV testing services: a systematic review and meta-analysis

2020

INTRODUCTION: Learning one’s HIV status through HIV testing services (HTS) is an essential step toward accessing treatment and linking to preventive services for those at high HIV risk. HTS may...

The role of targeted HIV screening in the emergency department: A scoping review

2020

BACKGROUND: Human immunodeficiency virus (HIV) infection continues to expand worldwide and a significant proportion of infection is still undiagnosed. Recent studies have addressed the impact and feasibility of ‘opt-out’ HIV...

Prevalence and incidence of hepatitis C virus infection in men who have sex with men: A systematic review and meta-analysis

2021

BACKGROUND: WHO has set targets for hepatitis C virus (HCV) elimination by 2030. We did a global systematic review of HCV prevalence and incidence in men who have sex with...

Platelet activation in adult HIV-infected patients on antiretroviral therapy: a systematic review and meta-analysis

2020

BACKGROUND: Antiretroviral therapy (ART) alters platelet reactivity, and as a consequence, patients living with HIV may be at an increased risk of cardiovascular disease (CVD). The current evidence on platelet...

Addressing unhealthy alcohol use and the HIV pre-exposure prophylaxis care continuum in primary care: A scoping review

2020

Individuals with unhealthy alcohol use are at increased risk for HIV acquisition and may benefit from receiving HIV pre-exposure prophylaxis (PrEP) in primary care settings. To date, literature synthesizing what...

Clinical impact of pretreatment human immunodeficiency virus drug resistance in people initiating nonnucleoside reverse transcriptase inhibitor-containing antiretroviral therapy: A systematic review and meta-analysis

2020

BACKGROUND: Increased access to antiretroviral therapy (ART) has resulted in rising levels of pretreatment human immunodeficiency virus drug resistance (PDR). This is the first systematic review and meta-analysis to assess...

Effect of syphilis infection on HIV acquisition: A systematic review and meta-analysis

2020

Objectives: Co-infection of syphilis and HIV remains hard to manage and its morbidity shows a rising tendency. Syphilis has been associated with increased risk of HIV acquisition in high-risk groups,...

Molecular epidemiology of human papillomavirus among HIV infected women in developing countries: Systematic review and meta-analysis

2020

Background: Although, there is a variable burden of human papillomavirus (HPV) in women infected with HIV in developing countries, there are few studies that attempted to surmise such variable evidences....

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