Category Archives: Population(s)
Comparative efficacy, tolerability and safety of dolutegravir and efavirenz 400mg among antiretroviral therapies for first-line HIV treatment: A systematic literature review and network meta-analysis
Background: To inform World Health Organization (WHO) global guidelines, we updated and expanded the evidence base to assess the comparative efficacy, tolerability, and safety of first-line antiretroviral therapy (ART) regimens....
The effect of probiotics, prebiotics, and synbiotics on cd4 counts in HIV-infected patients: A systematic review and meta-analysis
BACKGROUND: Probiotics as a potential adjuvant therapy may improve the restoration of the intestinal CD4(+) T-cell population in HIV-infected patients, whereas findings from clinical trials are inconsistent. This systematic review...
Prevalence of pretreatment HIV drug resistance in key populations: A systematic review and meta-analysis
Introduction: WHO’s 2019 report on HIV drug resistance (HIVDR) documents a high prevalence of pretreatment drug resistance (PDR) among populations initiating first-line antiretroviral therapy (ART) in low- and middle-income countries...
Frequency of falls and associated risk factors in people living with HIV: a systematic review with meta-analysis and meta-regression
BACKGROUND: Falls are considered predictive marker of poorer outcomes for people living with HIV. However, the available evidences on the predictive value of falls are controversial. Our aim is to...
Health and Health Care Access Barriers Among Transgender Women Engaged in Sex Work: A Synthesis of U.S.-Based Studies Published 2005-2019
Purpose: Transgender women (TW) are likely to experience job discrimination and engage in commercial sex transactions. As a group, they have the highest risk for HIV/AIDS. However, little is known...
Prevalence of occupational exposure to needle-stick injury and associated factors among healthcare workers of developing countries: Systematic review
BACKGROUND: Healthcare workers are at high risk of infection from blood-borne pathogens, such as Hepatitis B and C Virus, and Human Immunodeficiency. Occupational exposure to needle-stick injuries (NSIs) continue to...
Immunogenicity of pneumococcal vaccination in HIV infected individuals: A systematic review and meta-analysis
Background: The objective of this systematic review and meta-analysis was to summarise the literature regarding the immunogenicity of pneumococcal conjugate vaccines (PCV) and pneumococcal polysaccharide vaccines (PPSV) in adult people...
Eliciting Preferences for HIV Prevention Technologies: A Systematic Review
BACKGROUND: Many human immunodeficiency virus (HIV) prevention technologies (pre-exposure prophylaxis, microbicides, vaccines) are available or in development. Preference elicitation methods provide insight into client preferences that may be used to...
Factors associated with antiretroviral treatment failure among people living with HIV on antiretroviral therapy in resource-poor settings: A systematic review and metaanalysis
BACKGROUND: Despite the increase in the number of people accessing antiretroviral therapy (ART), there is limited data regarding treatment failure and its related factors among HIV-positive individuals enrolled in HIV...
Impact of COVID-19 in patients with concurrent co-infections: A systematic review and meta-analyses
The burden and impact of secondary superadded infections in critically ill coronavirus disease 2019 (COVID-19) patients is widely acknowledged. However, there is a dearth of information regarding the impact of...
