Category Archives: Population(s)
Clinical and public health implications of HIV-genetic diversity and drug resistance mutations in Angola: A systematic review
HIV-1 genetic diversity and drug resistance mutations (DRMs) remain a public health concern mainly in low- and middle-income countries. In this review, we estimated the HIV-1 molecular evolution over the...
What constitutes a palliative care need in people with serious illnesses across Africa? A mixed-methods systematic review of the concept and evidence
BACKGROUND: Clarity on what constitutes a palliative care need is essential to ensure that health systems and clinical services deliver an appropriate response within Universal Health Coverage. AIM: To synthesise...
HIV-tuberculous meningitis co-infection: A systematic review and meta-analysis
Human immunodeficiency virus (HIV)-infected persons are at a higher risk of developing Tuberculous meningitis (TBM). We aimed to estimate the prevalence of TBM-HIV co-infection. We systematically searched Pubmed/Medline, Embase and...
Effectiveness of opiate substitution treatment in reducing HIV risk behaviors among African Caribbean and Black people: A systematic review
OBJECTIVE: The objective of this systematic review is to identify, appraise, and synthesize the best available evidence on the effectiveness of opioid substitution treatment in reducing HIV risk behavior among...
Experienced homophobia and HIV infection risk among U.S. gay, bisexual, and other men who have sex with men: A meta-analysis
Purpose: Experienced homophobia-negative treatment and perceptions that gay, bisexual, and other men who have sex with men (MSM) encounter because of their sexual orientations-may promote HIV infection among MSM. We conducted...
Rates and risk factors for suicidal ideation, suicide attempts and suicide deaths in persons with HIV: A systematic review and meta-analysis
BACKGROUND: People living with HIV/AIDS (PLWHA) must contend with a significant burden of disease. However, current studies of this demographic have yielded wide variations in the incidence of suicidality (defined...
Worldwide relative smoking prevalence among people living with and without HIV
Objective and design: People living with HIV (PLH) suffer disproportionately from the chronic diseases exacerbated by smoking tobacco. We performed a systematic review and meta-analysis to establish the relative prevalence of...
The impact of age on antiretroviral drug pharmacokinetics in the treatment of adults living with HIV
INTRODUCTION: People living with HIV (PLWH) are aging and will receive life-long treatment: despite substantial improvement in drug efficacy and tolerability, side effects still occur and they can blunt antiretroviral...
The prevalence of depression among adolescent with HIV/AIDS: A systematic review and meta-analysis
BACKGROUND: Depression is particularly common among adolescents with HIV/AIDS and has been associated with disruption of the important developmental process, subsequently leading to a wide range of negative mental, physical...
HIV infections and food insecurity among pregnant women from low- and middle-income countries: A systematic review and meta-analysis
There are few studies on the occurrence of food insecurity (FI) in pregnant women living with HIV/AIDS (PrWLWHA). Our objective was to estimate the prevalence of food insecurity among PrWLWHA...
Efficacy and acceptability of different anti-fungal interventions in oropharyngeal or esophageal candidiasis in HIV co-infected adults: A pilot network meta-analysis
BACKGROUND: Oropharyngeal/esophageal candidiasis are the most common opportunistic infections observed in patients with human immunodeficiency virus (HIV). While the commonly recommended treatment is fluconazole, relapse of oropharyngeal or esophageal candidiasis...
