Category Archives: Population(s)
Choosing between dual and three-drug antiretroviral therapy in aging and comorbid people with HIV: A narrative review
The widespread use of combination antiretroviral therapy has transformed HIV infection into a chronic condition, with life expectancy of people with HIV (PWH) approaching that of the general population when...
Dysregulated metabolism in people living with HIV in the modern ART-era: A systematic review of targeted metabolomics studies
HIV remains a significant public health issue, with 1.3 million new infections and 630,000 deaths annually, and 40.8 million people living with HIV (PLHIV) globally in 2024. Although antiretroviral therapy...
Maternal-to-child-transmission of human immunodeficiency virus in maternal preterm premature rupture of the membranes: A systematic review
Aim: Preterm premature rupture of membranes (PPROM) in the context of maternal human immunodeficiency virus (HIV) infection poses a significant clinical dilemma, as clinicians must balance the risks of prematurity with...
Barriers and facilitators to oral HIV pre-exposure prophylaxis use in Australia: A scoping review comparing findings to Canada, New Zealand, and the United Kingdom
Oral HIV pre-exposure prophylaxis (PrEP) is highly effective, yet various barriers limit its potential as a HIV prevention strategy. This scoping review aimed to identify and quantify determinants of oral...
Perinatal outcomes associated with antiretroviral therapy for pregnant women living with HIV: An umbrella review
Background: The World Health Organization recommends antiretroviral therapy (ART) for pregnant women living with HIV (WLHIV), the vast majority of whom reside in sub-Saharan Africa. In recent years, many systematic reviews,...
Effectiveness of digital interventions in reducing chemsex-related health risks among mem who have sex with men (MSM): A systematic review
Chemsex among men who have sex with men (MSM) has emerged as a significant public health concern, creating an urgent need for effective harm-reduction strategies. Digital platforms are becoming a...
Implementation of therapeutic adherence in adult patients diagnosed with the human immunodeficiency virus: A systematic review
OBJECTIVES: To systematically map and summarize the available knowledge on interventions that promote medication adherence among adult HIV patients and to describe the current state of the art regarding the...
Perspective of people living with HIV and healthcare workers on the uptake, barriers, and benefits of multimonth dispensing: A qualitative systematic review
INTRODUCTION: Multimonth dispensing (MMD) is a strategy in the HIV care continuum for people living with HIV (PLWH), especially for those who are virally suppressed. With the increase in MMD...
Effects of targeted interventions on HIV testing, knowledge and sexual risk behaviours among long-distance truck drivers: A systematic review and meta-analysis
Objectives We aimed to systematically summarise and quantify the empirical evidence on targeted interventions and their effects on various HIV prevention outcomes for long-distance truck drivers (LDTDs) globally. Design A...
Simulation modeling for the design and evaluation of HIV drug resistance interventions: A systematic review of literature
Background The utility of antiretroviral therapy (ART) in the management of human immunodeficiency virus (HIV) is being challenged by growing HIV drug resistance (HIVDR). Although simulation modelling is useful for...
Integration of HIV, Hepatitis B, and C, and sexually transmitted infections services: A scoping review of the benefits and challenges
BACKGROUND: Integrating clinical programs and services is a cost-effective approach that can improve health and system outcomes. This review aimed to provide an overview of the benefits and challenges of...
Interventions to improve access to sexual and reproductive health services for adolescents living with HIV in sub-Saharan Africa: A scoping review
OBJECTIVE: Adolescents living with HIV (ALHIV) face barriers to accessing sexual and reproductive health (SRH) services, negatively affecting their health and quality of life. These challenges are particularly pronounced in...
