Category Archives: Population(s)
Clinical trials of broadly neutralizing monoclonal antibodies in people living with HIV—A review
Introduction HIV-1 remains a major global health challenge, impacting approximately 39 million people worldwide. Although antiretroviral therapy has substantially reduced HIV incidence and enhanced the quality of life for those living...
Experiences of older people living with human immunodeficiency virus comorbidity attending coordinated healthcare services
BACKGROUND: Older people living with human immunodeficiency virus (OPLWHIV) on antiretroviral therapy are aging and face an increased risk of non-communicable diseases. The burden is costly and demands sustainable care...
The role of digital tools in enhancing antiretroviral therapy adherence among adolescents and young adults with HIV: A systematic review of randomized controlled trials
Background: Adolescents and Young Adults (AYA) face challenges in maintaining antiretroviral therapy (ART) adherence, necessitating the need for targeted and innovative interventions. Digital tools have shown potential in improving ART adherence...
Insights into gastrointestinal manifestation of human immunodeficiency virus: A narrative review
Human immunodeficiency virus (HIV) modifies CD4-positive cells, resulting in immunodeficiency and a wide range of gastrointestinal (GI) manifestations. The burden of HIV-related GI illnesses has significantly evolved with the widespread...
Global, regional, and national estimates of hepatitis C virus (HCV) infection incidence among people who inject drugs and number of new annual HCV infections attributable to injecting drug use: A multi-stage analysis
Background: Measuring progress towards the WHO 2030 target for hepatitis C virus (HCV) elimination among people who inject drugs (PWID)-an incidence of two or fewer infections per 100 person-years-has been challenging...
An international compendium of health state utilities in people with HIV: A systematic review
Purpose: Measuring health-related quality of life across different health states for people with HIV (PWH) using direct or indirect preference-based values can inform decision-analytic models evaluating cost-effectiveness of different care strategies....
Exercise interventions conducted among individuals with co-occurring HIV and unhealthy substance use: A systematic review
Unhealthy substance use and physical inactivity are prevalent co-occurring risk factors for morbidity and mortality among people with HIV (PWH). Evidence-based exercise interventions targeting both risk factors are limited. We...
Ptosis in human immunodeficiency virus-infected patients under long-term antiretroviral treatment
OBJECTIVE: To present cases of ptosis in HIV-1 patients on long-term antiretroviral therapy (ART) and review the existing literature. METHODS: Five HIV-1-positive patients with slowly progressive bilateral ptosis underwent a...
PrEP uptake and utilisation among adolescent girls and young women in Sub-Saharan Africa: A scoping review
Adolescent girls and young women (AGYW) in sub-Saharan Africa (SSA) are disproportionately affected by HIV. Despite the effectiveness of oral pre-exposure prophylaxis (PrEP) in preventing HIV, uptake and effective utilisation...
Facilitators and barriers to Hiv pre-exposure prophylaxis adherence and retention among young men who have sex with men: A meta-ethnographic scoping review
Retention and adherence to daily oral pre-exposure prophylaxis (PrEP) are critical for effective HIV prevention; however, YMSM exhibit lower rates of both compared to other populations. This is important because...
Assessment tools for evaluating pharmacy students’ knowledge on HIV prophylaxis: A scoping review
OBJECTIVES: This study aimed to identify and evaluate instruments used to measure pharmacy students’ knowledge of HIV prophylaxis, focusing on both preexposure prophylaxis (PrEP) and postexposure prophylaxis. METHODS: A systematic...
Drug-drug interactions in transgender patients receiving antiretroviral and hormonal therapy: A systematic review of clinical studies and reports
Transgender individuals, whose gender identity differs from their assigned sex at birth, often undergo pharmacotherapy, including hormone therapy (HT), as part of their gender-affirming care. This pharmacotherapy, particularly when combined...
