Category Archives: Population(s)
Systematic review and meta-analysis of global prevalence of HBsAg and HIV and HCV antibodies among people who inject drugs and female sex workers
The main objective of this study was to evaluate the prevalence of human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS), hepatitis C virus (HCV) and hepatitis B virus (HBV) and their co-infections...
Cryptococcal antigenemia and its predictors among HIV infected patients in resource limited settings: A systematic review
BACKGROUND: Cryptococcosis is an opportunistic fungal infection that primarily affects people with advanced HIV/AIDS and is an important cause of morbidity and mortality around the globe. By far the most...
Injecting risk behaviours amongst people who inject drugs: A global multi-stage systematic review and meta-analysis
BACKGROUND: Injecting risk behaviour, such as receptive sharing of injecting equipment and/or re-using one’s equipment, is associated with bloodborne virus transmission and infections in people who inject drugs (PWID). We...
Direct-acting antivirals for HCV treatment in older patients: A systematic review and meta-analysis
The advent of highly effective and well-tolerated direct antiviral antivirals (DAAs) has dramatically changed the landscape of chronic hepatitis C. The effect of DAAs in older adults is difficult to...
Tuberculosis and its association with CD4(+) T cell count among adult HIV positive patients in Ethiopian settings: A systematic review and meta-analysis
BACKGROUND: Tuberculosis (TB) and HV have been intertwined and makeup a deadly human syndemic worldwide, especially in developing countries like Ethiopia. Previous studies have reported different TB incidences and its...
The effectiveness of electronic health interventions for promoting HIV-preventive behaviors among men who have sex with men: Meta-analysis based on an integrative framework of design and implementation features
BACKGROUND: The disproportionately high prevalence of HIV among men who have sex with men (MSM) is a global concern. Despite the increasing utilization of electronic health (eHealth) technology in the...
mHealth and opportunities in anti-retroviral adherence in HIV, a diverse group of patients with diverse and unique opportunities: A narrative review
BACKGROUND: Antiretrovirals (ARVs) are key in the management of human immunodeficiency virus (HIV). While no cure exists, ARVs help patients live healthy lives and prevent transmission to others. However, adherence...
Cryptosporidiosis in HIV-positive patients and related risk factors: A systematic review and meta-analysis
Cryptosporidium is one of the major causes of diarrhea in HIV-positive patients. The aim of this study is to systematically review and meta-analyze the prevalence of Cryptosporidium in these patients....
The prevalence of cryptococcal antigen (CrAg) and benefits of pre-emptive antifungal treatment among HIV-infected persons with CD4+ T-cell counts < 200 cells/muL: Evidence based on a meta-analysis
BACKGROUND: Current WHO guidelines (2018) recommend screening for cryptococcal antigen (CrAg) in HIV-infected persons with CD4+ T cell counts< 100 cells/muL, followed by pre-emptive antifungal therapy among CrAg positive (CrAg+)...
