Category Archives: Population(s)

Pharmacogenetic markers: A path toward individualized HIV therapy

2019

INTRODUCTION Approximately 73% of persons with HIV who receive antiretroviral therapy in Cuba are in viral suppression. The non-response of the remaining 27% could be due to several factors including...

Utilizing a life course approach to examine HIV risk for black adolescent girls and young adult women in the United States: A systematic review of recent literature

2020

Objective: Black female youth have been disproportionately burdened by the HIV epidemic. Emerging literature suggests that individual and social-structural factors may uniquely increase HIV risk within this population during key...

HIV-1 subtype frequency in Northeast Brazil: A systematic review and meta-analysis

2020

Information on human immunodeficiency virus (HIV) molecular epidemiology is required to verify HIV/AIDS (acquired immune deficiency syndrome) epidemic dynamics in different regions, as well as provide support for response to...

Depression and HIV disease progression: A mini-review

2019

Background: Depression is the most common mental disorder and a leading cause of disability, which commonly presents unexplained psychological and physical symptoms. Depression and HIV/AIDS are commonly comorbid. This review...

Fracture-related infections in HIV infected patients: A systematic review and meta-analysis

2020

Aim: To conduct a systematic review and meta-analysis comparing the incidence of fracture-related infections (FRI) following surgical management of closed and open fractures in HIV-positive and HIV-negative patients. Methods: A...

Neurocysticercosis and HIV Infection: What can we learn from the published literature?

2019

OBJECTIVE: Infections caused by the human immunodeficiency virus (HIV) and by the larvae of Taenia solium (i.e., cysticercosis) are still widespread in many developing countries. Both pathologies modify host immune...

Treating progressive disseminated histoplasmosis in people living with HIV

2020

BACKGROUND: Progressive disseminated histoplasmosis (PDH) is a serious fungal infection that affects people living with HIV. The best way to treat the condition is unclear. OBJECTIVES: We assessed evidence in...

Community engagement interventions for communicable disease control in low- and lower- middle-income countries: Evidence from a review of systematic reviews

2020

BACKGROUND: Community engagement (CE) interventions include a range of approaches to involve communities in the improvement of their health and wellbeing. Working with communities defined by location or some other...

Barriers to HIV testing uptake among men in sub-Saharan Africa: A scoping review

2020

Introduction: HIV testing among men remains low globally and in sub-Saharan Africa (SSA) in particular, when compared with their female counterparts. The aim of this study was to synthesis evidence...

Intimate partner violence (IPV) against HIV-positive women in sub-Saharan Africa: A mixed-method systematic review and meta-analysis

2020

OBJECTIVES: To systematically analyze and summarize the literature on intimate partner violence (IPV) against HIV-positive women in sub-Saharan Africa (SSA) and to identify their risk factors for IPV. METHOD: A...

Pharmacokinetics, placental and breast milk transfer of antiretroviral drugs in pregnant and lactating women living with HIV

2019

BACKGROUND: Remarkable progress has been achieved in the identification of HIV infection in pregnant women and in the prevention of vertical HIV transmission through maternal antiretroviral treatment (ART) and neonatal...

Paradoxes in the phenotype, frequency and roles of myeloid-derived suppressor cells during HIV infection

2020

Myeloid-derived suppressor cells (MDSCs) are heterogeneous groups of pathologically activated myeloid cells with potent immunosuppressive function. Due to their role in negatively regulating the immune system, MDSCs have been strongly...

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