Category Archives: Population(s)
The safety and efficacy of immune checkpoint inhibitors in patients with advanced cancers and pre-existing chronic viral infections (Hepatitis B/C, HIV): A review of the available evidence
The treatment paradigm of several cancers has dramatically changed in recent years with the introduction of immunotherapy. Most oncology trials involving immune checkpoint inhibitors (ICIPs) have routinely excluded patients with...
Stroke and systemic thromboembolism prevention in people living With human immunodeficiency virus with atrial fibrillation: A review of its implications for clinical practice
In the last few decades, types of diseases affecting people living with human immunodeficiency virus (PLHIV) have shifted as the population ages, with cardiovascular disease becoming a leading cause of...
Possible benefits of providing safe supply of substances to people who use drugs during public health emergencies such as the COVID-19 pandemic
Key take-home messages Safe supply is an approach that focuses on saving lives by prescribing pharmaceutical grade substances such as opioids and stimulants to individuals at risk of overdose and...
The interplay of HIV and human papillomavirus-related cancers in sub-Saharan Africa: Scoping review
BACKGROUND: People living with HIV (PLHIV) are at a high risk of developing HPV-related cancers. HPV-related malignancies occur frequently and/or are high among PLHIV, with cervical cancer as a designated...
The effectiveness of treatment supporter interventions in antiretroviral treatment adherence in sub-Saharan Africa: A systematic review and meta-analysis
This systematic review and meta-analysis evaluated the effectiveness of treatment supporter interventions (TSI) in improving ART adherence and viral suppression among adults living with HIV (PLWH) in sub-Saharan Africa. This...
Interventions to improve antiretroviral therapy adherence among adolescents and youth in low- and middle-income countries: A systematic review 2015-2019
Adolescents and youth living with HIV have poorer antiretroviral treatment (ART) adherence and viral suppression outcomes than all other age groups. Effective interventions promoting adherence are urgently needed. We reviewed...
Therapeutic use of cannabis and cannabinoids: An evidence mapping and appraisal of systematic reviews
BACKGROUND: Although cannabis and cannabinoids are widely used with therapeutic purposes, their claimed efficacy is highly controversial. For this reason, medical cannabis use is a broad field of research that...
