Category Archives: Population(s)
Antiviral therapy for cytomegalovirus retinitis: A systematic review and meta-analysis
Cytomegalovirus retinitis (CMVR) is a significant cause of blindness in patients with advanced acquired immunodeficiency syndrome (AIDS). There are no established guidelines for its treatment, resulting in varied antiviral approaches....
Skin cancer in patients who are co-infected with HIV/ HBV or HIV/HCV: A systematic review
Skin cancer, the most common cancer in the United States, has been well-described in the literature to be associated with environmental factors including ultraviolet (UV) radiation. However, the effect of...
The impact of undernutrition and anemia on HIV-related mortality among children on ART in sub-Saharan Africa: A systematic review and meta-analysis
BACKGROUND: Although there have been significant advancements in providing HIV-infected children with access to antiretroviral therapy (ART), the mortality rates have remained unacceptably high. Inadequate nutrient intake or absorption is...
Detection of new HIV cases under epidemic control—When is it the right time to review HIV testing algorithms for countries nearing the 95-95-95 milestones? Case study—Bostwana
Background: Accurate diagnosis of human immunodeficiency virus (HIV) infection is dependent on using established national HIV testing algorithm. The purpose of this study was to review published articles to identify,...
Interventions to ensure access to and continuity of HIV care for international migrants: An evidence synthesis
International migrants, especially those belonging to key populations, face a considerable HIV burden. However, continuity of HIV care for this group is often challenged along the migration route. We assess...
Impact of the COVID-19 pandemic on the HIV care continuum and associated factors in middle-income countries: A mixed-methods systematic review
INTRODUCTION: The HIV care continuum during the COVID-19 era faced specific challenges. The pandemic, affecting the delivery of HIV care, exacerbated existing healthcare inequities and vulnerabilities in middle-income countries with...
Patient and public involvement in HIV research: A mapping review and development of an online evidence map
INTRODUCTION: Increasing evidence indicates the benefits of patient and public involvement (PPI) in medical research, and PPI is increasingly expected by funders and publishers. We conducted a mapping review of...
A scoping review of observational research on cannabis use for symptom management in HIV and cancer: Implications for cannabis nursing
Background: People with HIV have a higher risk of developing non-AIDS-defining cancers in older age, leading to a significant population living with two conditions, HIV and cancer. There is an increasing...
Efficacy and safety of systematic corticosteroids treatment among HIV-positive patients with tuberculosis: A systematic review and meta-analysis of randomized controlled trials
INTRODUCTION: The efficacy and safety of corticosteroids in patients with human immunodeficiency virus (HIV) and tuberculosis (TB) remain controversial. METHOD: PubMed, Embase, Web of Science, and the Cochrane Database were...
Geospatial distribution of HIV seroprevalence among blood donors in South Asian countries: A systematic review and meta-analysis
The reliance on replacement blood donors in developing countries has led to an increased prevalence of transfusion-transmitted infections (TTIs), including HIV. This systematic review and meta-analysis aimed to assess the...
Burden of mortality and its predictors among TB-HIV co-infected patients in Ethiopia: Systematic review and meta-analysis
BACKGROUND: Human immunodeficiency virus (HIV) and tuberculosis (TB) are still the two major deadly pandemics globally, causes 167,000 deaths in 2022. The two lethal combinations pose a substantial challenge to...
Gut microbiome alteration in HIV/AIDS and the role of antiretroviral therapy—A scoping review
(1) Background: The gut microbiota plays a crucial role in chronic immune activation associated with human immunodeficiency virus (HIV) infection, acquired immune deficiency syndrome (AIDS) pathogenesis, non-AIDS-related comorbidities, and mortality...
