Category Archives: Population(s)

Retention in HIV care among Southeast Asian people living with HIV: A systematic review and meta-analysis

2025

Background Despite the effectiveness of antiretroviral therapy (ART) in reducing HIV-related morbidity and mortality, the retention of HIV care remains suboptimal in Southeast Asia. Objective This systematic review and meta-analysis...

Machine learning for personalized risk assessment of HIV, syphilis, gonorrhoea and chlamydia: A systematic review and meta-analysis

2025

Background Machine learning (ML) shows promise for sexually transmitted infection (STI) risk prediction, but systematic evidence of its effectiveness remains fragmented. Methods We systematically searched six electronic databases, three preprint...

Associations between depressive symptoms and memory functions in persons with HIV: A systematic review and meta-analysis

2025

Episodic memory impairment can persist in persons with HIV (PWH) despite treatment. Depression is among the most prevalent comorbidities in HIV. Changes to brain regions involved in episodic memory like...

Estimating the effect of maternal viral load on perinatal and postnatal HIV transmission: A systematic review and meta-analysis

2025

Background Although a growing body of evidence supports zero risk of sexual HIV transmission from a person with sustained virological suppression, known as U=U (undetectable equals untransmittable), data have been...

The diagnostic significance of the C-reactive protein (CRP) in HIV/TB coinfection: A systematic review and meta-analysis

2025

Background Drug-resistant Mycobacterium tuberculosis strains have challenged efforts to combat tuberculosis (TB), a major global killer. C-reactive protein (CRP) shows promise as a biomarker for TB screening, particularly in HIV-positive...

A scoping review on HCV screening strategies: Population to screen and the test types

2025

BACKGROUND: Hepatitis C virus (HCV) is a genetically diverse blood-borne pathogen causing liver inflammation and damage. It is one of the global public health problems responsible for claiming thousands of...

Evaluating predictive performance, validity, and applicability of machine learning models for predicting HIV treatment interruption: A systematic review

2025

Background HIV treatment interruption remains a significant barrier to achieving global HIV/AIDS control goals. Machine learning (ML) models offer potential for predicting treatment interruption by leveraging large clinical data. Understanding...

HIV infection and antiretroviral therapy impair liver function in people living with HIV: Systematic review and meta-analysis

2025

Background: The use of antiretroviral therapy (ART) has improved the lives of people living with HIV (PLWH). However, its use is associated with secondary complications, notably hepatotoxicity. This systematic review and...

Prevalence of and risk factors for suicidal ideation among perinatal women with HIV infection: A systematic review, meta-analysis, and meta-regression

2025

Background The prevalence of suicidal ideation (SI) among HIV-positive pregnant women is a complex issue influenced by multiple risk factors. By addressing these risk factors and focusing on vulnerable regions,...

Worldwide epidemiology of Cyclospora cayetanensis in HIV/AIDS patients: A systematic review and meta-analysis

2025

BACKGROUND: Cyclospora cayetanensis is a coccidian protozoan parasite belonging to the phylum Apicomplexa. This systematic review and meta-analysis aimed to assess the prevalence and risk factors of C. cayetanensis in...

HIV, hepatitis, and syphilis self-testing among adolescents and young adults: A systematic review and meta-analysis

2025

Background: Adolescents and young adults (AYA) make up a significant share of the world’s burden of HIV and other sexually transmitted infections (STI). Self-testing can increase testing coverage and strengthen the...

Meta-analysis of TB & HIV co-infection mortality rate in sub-Saharan African children, youth, and adolescents

2025

Background Despite the effectiveness of antiretroviral treatment (ART) in reducing morbidity and mortality, children and adolescents with co-infections face an elevated risk of death due to their young age and...

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